Dr Aygün Yörükoğlu

Thank you all for playing along. This is indeed usual ductal hyperplasia involving a complex sclerosing lesion. This case illustrates how benign processes can be alarming both radiologically (spiculated mass) and histologically (irregular nests with compact florid epithelial proliferation). Clues to the benign nature of this lesion include distinct periductal sclerosis, a subtle but visible myoepithelial layer, variability in nuclear size while maintaining a small overall diameter, and uneven placement and overlapping of the proliferating cells. It helps to be reminded that none of these features is sufficient by itself. No feature is EVER sufficient by itself. One piece of evidence is never enough. If it were, then many an innocent soul would be wrongly convicted, and many a guilty soul would falsely absolved. @washupathedu @wusm_pathology #breastpath #PathTwitter