@probstMD

Academic Emergency Physician. Director of Adult Research @columbiaEM. Syncope researcher. Views are my own and not my employer's.

 Manhattan, NY
Joined April 2017
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163Media
Very pleased to share our publication validating the FAINT and Canadian Syncope Scores for ED patients with unexplained syncope in @JAMANetworkOpen Both showed excellent discrimination. The FAINT score outperformed physician gestalt w/r/t sensitivity. jamanetwork.com/journals/jam…

Validation of 2 Syncope Risk Scores and Comparison With Physician Risk Estimation

This cohort study validates the ability of 2 risk-stratification tools to estimate 30-day serious outcomes in patients with syncope or presyncope and compares their performance with unstructured...

jamanetwork.com
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Which ED patients with unexplained syncope need an Echo? ❤️‍🩹 There's a score for that: The ROMEO Score. Just validated in age 40+ . Now out in @AcademicEmerMed @probstMD Read it here: onlinelibrary.wiley.com/doi/…
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Which ED patients with unexplained syncope need an Echo? ❤️‍🩹 There's a score for that: The ROMEO Score. Just validated in age 40+ . Now out in @AcademicEmerMed (Risk Of Major Echocardiography findings in Older adults with syncope) Score below... onlinelibrary.wiley.com/doi/…

Predicting Echocardiography Findings in Adults Presenting to the Emergency Department With Syncope:...

Background Syncope is common in the Emergency Department (ED) and can be associated with structural heart disease (SHD). Transthoracic echocardiography (TTE) is commonly ordered to assess for SHD. ...

onlinelibrary.wiley.com
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1) history of heart failure 2) history of coronary artery disease 3) abnormal ECG 4) elevated Hs-TnT 5) elevated NT-Pro BNP A ROMEO score of zero had ▶️Sensitivity: 98.9% ▶️NPV: 98.6% for clinically significant findings on echo.
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Marc Probst, MD retweeted
Pierre Elias, MD@PierreEliasMDJun 22
We invented a new biomarker for cardiovascular disease. The New York Times tells our story (link in comments).
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Marc Probst, MD retweeted
JAMA Network Open@JAMANetworkOpenMay 21
Both the Canadian Syncope Risk Score and FAINT score identified emergency department patients at low risk for serious outcomes, with FAINT showing higher sensitivity than physicians for serious cardiac outcomes. ja.ma/499syAD
The image shows ROC curves and calibration plots. A and B are ROC curves for \"FAINT@1\"/\"SCO@2\" and \"CSRS@3\"/\"SAO@4\" with AUROC and PER values. C and D show calibration plots for \"FAINT@1\" and \"CSRS@3\" scores, plotting observed vs. estimated risk.

ALT The image shows ROC curves and calibration plots. A and B are ROC curves for \"FAINT@1\"/\"SCO@2\" and \"CSRS@3\"/\"SAO@4\" with AUROC and PER values. C and D show calibration plots for \"FAINT@1\" and \"CSRS@3\" scores, plotting observed vs. estimated risk.

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Elements of the FAINT score: F - History of heart Failure (+1) A - History of cardiac Arrhythmia (+1) I - Initial abnormal ECG result (+1) N - Elevated NT-proBNP (+2) T - Elevated high-sensitivity Troponin (+1)
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FAINT score of zero be used to identify ED patients at very-low risk of serious cardiac outcomes at 30 days.
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Congratulations to Dr. Chernick & Dr. Probst for their recent publication evaluating the efficacy of a digital patient decision aid, "STIckER" in increasing STI testing among adolescents and young adults in the ED! Read more pubmed.ncbi.nlm.nih.gov/4213…
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Congratulations to Drs. Dana Sacco, Ed Suh, and Marc Probst on their recent publication in @AnnalsofEM examining sex-differences in clinical outcomes after syncope @probstMD annemergmed.com/article/S019…
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Multidose Ondansetron after Emergency Visits in Children with Gastroenteritis | @NEJM nejm.org/doi/10.1056/NEJMoa2…

Multidose Ondansetron after Emergency Visits in Children with Gastroenteritis | NEJM

Ondansetron improves outcomes when administered in emergency departments to children with acute gastroenteritis–associated vomiting. It is commonly prescribed at discharge to reduce symptoms, but e...

nejm.org
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Congrats to Drs. Ed Suh, Dana Sacco and Marc Probst, on their recent publication in @AnnalsofEM comparing clinical management and outcomes among ED patients with syncope vs. presyncope @probstMD Read it here: authors.elsevier.com/c/1lp-v…
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Marc Probst, MD retweeted
SAEM@SAEMonline25 Sep 2025
This #StopTheStigmaEM event will examine the role of peer support in helping colleagues through complex realities and highlight tips for creating a culture where clinicians can speak openly about their struggles and receive meaningful support. Register: ow.ly/SJH450WVgTf
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Marc Probst, MD retweeted
Jonathan Haidt
@JonHaidt24 Sep 2025
Here's the best 60 second PSA illustrating what we do to children when we give them a smartphone. We ask them to do the impossible. Join Smartphone Free Childhood! youtube.com/watch?v=h_xwJ5u9…
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Great to see NYP resident Eli Rogers presenting our work on validation of the Canadian Syncope Risk Score at #acep25 The score performed just as well for ED patients with presyncope as for those with syncope. @ACEPNation @ColumbiaEM @NYEmergency
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Among kids with AGE, ondansetron (Zofran) led to lower risk of moderate-to-severe gastroenteritis during the subsequent 7 days compared with placebo. New RCT in @NEJM nejm.org/doi/10.1056/NEJMoa2…

Multidose Ondansetron after Emergency Visits in Children with Gastroenteritis | NEJM

Ondansetron improves outcomes when administered in emergency departments to children with acute gastroenteritis–associated vomiting. It is commonly prescribed at discharge to reduce symptoms, but e...

nejm.org
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Come join our world-class team as we are recruiting for an Assistant Medical Director for the Pediatric Emergency Department at the NewYork-Presbyterian Children's Hospital of New York at Morgan Stanley in Manhattan and NewYork-Presbyterian Westchester in Bronxville! #pediatrics
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Marc Probst, MD retweeted
SAEM@SAEMonline3 Sep 2025
Help us fill NIH study sections with #EmergencyMedicine investigators by nominating yourself or another expert by September 30! With more EM investigators, there will be more opportunities for #EmergencyCare investigators to succeed. Learn more: ow.ly/1JX350WFzI4
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Marc Probst, MD retweeted
Eric Topol
@EricTopol2 Sep 2025
A nasal spray reduced the risk of Covid infections in a double blind, placebo controlled randomized trial jamanetwork.com/journals/jam…
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Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections: Phase 2 RCT ▶️OTC Allergy spray reduction COVID infections by 70%👃 jamanetwork.com/journals/jam…

Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections

This randomized clinical trial evaluates the efficacy of azelastine as a preexposure prophylaxis against SARS-CoV-2 and other respiratory pathogens.

jamanetwork.com
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