Memory stays strong in old age when this brain enzyme is active nature.com/articles/d41586-0…
Can GLP-1s heal the brain? Obesity drugs get a makeover for addiction and depression nature.com/articles/d41586-0…
Magdalena Sastre🇪🇺 retweeted
🧠 Migraine is a chronic neurological disorder that affects over 1 billion people globally each year, with women predominantly affected.
A new Seminar discusses typical symptoms, mechanisms, and treatment options: spkl.io/60107VNQg
Magdalena Sastre🇪🇺 retweeted
Esteban-García et al. show that using focused ultrasound combined with microbubbles to temporarily open the BBB over the substantia nigra reduces neuromelanin accumulation and associated pathological changes in a primate model of Parkinson’s disease. shorturl.at/AR6Wo
Karl Deisseroth, MD, PhD, winner of the Nobel Prize in Physiology or Medicine 2026, describes the science behind a study of intravitreal delivery of an AAV vector encoding a light-gated ion channel in 10 blind patients with advanced retinitis pigmentosa.
Read the editorial “Optogenetics in Sight”: nej.md/476T5x1

ALT An illustrated diagram from the editorial "Science behind the Study: Optogenetics in Sight" that shows direct and indirect translational optogenetics pathways. Panel A: Precise identification of causal cells and circuits allows principled targeting, whether through direct (left), indirect neuromodulatory (middle), or indirect medicinal (right) approaches. Panel B: Components of direct optogenetics for retinitis pigmentosa are shown, including the adeno-associated virus (AAV) (top), the light-projecting goggles (middle), and the channelrhodopsin protein (bottom). The NEJM identity sits at the bottom.
Can your brain grow new neurons? How researchers are solving a century-old puzzle nature.com/articles/d41586-0…
Magdalena Sastre🇪🇺 retweeted
Exclusive: “The instant I saw the picture my mouth fell open and my pulse began to race.” So wrote James Watson in The Double Helix: A Personal Account of the Discovery of the Structure of DNA, his controversial account of how he and Francis Crick deciphered the structure of DNA in 1953.
The image, now known as photograph 51, showed an elegant, symmetrical pattern of spots formed by x-rays diffracted from strands of DNA—the fingerprint of the molecule’s helical structure.
Rosalind Franklin, an x-ray crystallographer, had produced the image in the spring of 1952. But Watson’s 1968 book, amid other slights and sexist language directed at Franklin, implied the flash of insight was his alone.
Popular accounts still routinely suggest Franklin missed the significance of the photo. She never had a chance to challenge Watson’s dismissive narrative; she died of cancer in 1958, a decade before his memoir was released and became a bestseller.
But a new analysis of her notes on another x-ray image, which she made just days earlier using the same DNA sample, offers a firm rebuttal.
Learn more: scim.ag/4s7yQsV
Premio Nobel de Medicina para Karl Deisseroth, Peter Hegemann y Georg Nagel por la técnica que permite controlar el cerebro con luz elpais.com/ciencia/2026-10-0… via @el_pais
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#lipidtime: It's a lipid universe. Today in Nature we publish the Lipid Brain Atlas, the first map of membrane lipid composition across the entire mouse brain, a layer of organisation that cell-type and transcript maps had left out. #lipidomics #neuroscience #BrainAtlas
Las edades del cerebro: el atlas más detallado de la corteza prefrontal revela cómo cambia y envejece a lo largo de la vida elpais.com/ciencia/2026-09-2… via @el_pais
Map of brain ‘microproteins’ could offer new clues to Alzheimer’s disease nature.com/articles/d41586-0…
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@EnricMasNicola, ganador de @lavuelta a España: «Llevaba tiempo soñando y trabajando para esto» ultimahora.es/deportes/otros…
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“An exceptional moment” 🫶
Enric Mas and his team are ROARED home by the adoring Spanish crowd 🇪🇸❤️
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El ciclista mallorquín firma una lección de poderío y madurez para inscribir su nombre en el palmarés de su primera 'grande', superando a Roglic y haciendo bueno su quinto podio
ultimahora.es/deportes/otros…
Enric Mas y el laurel de la perseverancia: el mallorquín gana la Vuelta elpais.com/deportes/ciclismo…
The most successful early-career researchers often rely on a network of mentors who each have different roles — from advising on research and grants to making professional introductions and providing emotional support
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