Interested in cancer and regeneration. @JCChildsFund fellow @LabJacks. PhD @BBS_Harvard and @KevinHaigisLab. BA @CarletonCollege, also on @bing-shui.bsky.social
Boston, MA
Joined July 2012
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Amazing work showcasing how applying new technologies can unlock previously inaccessible biological insights!
Comprehensive fate mapping of C. elegans transformed our understanding of development by revealing how coordinated fate decisions generate a complex organism.
In our paper out today in @CellCellPress , we take a major step toward extending this vision to mammalian development.
sciencedirect.com/science/ar…
Bing Shui retweeted
Our new paper is out in Genes & Development! We found that a small domain in PRC2 — the SBD — isn't just structural scaffolding. It's a mechanical switch that powers the whole complex. Remove it, and cancers driven by EZH2 mutations stop growing. 🧵
🆕 ADVANCE ONLINE 🆕
RESEARCH PAPER: The conserved N-terminal SANT1-binding domain (SBD) of EZH2 regulates PRC2 activity
By Patriotis et al., and the late David Allis
➡️ ow.ly/YqbP50YNGZu
@ael2b @RockefellerUniv @epicypher
#epigenetic #histone #polycomb #lymphoma
Bing Shui retweeted
BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
Bing Shui retweeted
⭐ My lab at @DanaFarber is #hiring a #Postdoc! Our research spans disciplines including theranostics, molecular- and radio-biology. We are seeking candidates with a interest in radiation-induced DNA damage, cancer bio, and translational research🧫🧪☢️
tiny.cc/14ilzz
I’m honored to be among the 2024 class of the @JCChildsFund fellows! Excited to continue exploring the intersection between cancer and regeneration @LabJacks. Can’t wait to learn about the diverse medical research from all the other fellows.
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Incredibly grateful for all the support from my mentors @LabJacks @KevinHaigisLab @aventura71 and Dr. Richard Gregory!
Bing Shui retweeted
⭐ My lab is hiring a #postdoc! If you passionate about developing imaging technologies and theranostic agents to improve the detection, evaluation, and treatment of cancer, consider applying 🧫🧪☢️💡
More info/apply:
tiny.cc/0vyayz
Please RT #molecularimaging
Bing Shui retweeted
Our work on studying chromatin context-dependent regulation of prime editing is officially out on @Cell.
cell.com/cell/fulltext/S0092…
Bing Shui retweeted
My lab is hiring a Research Technician in the Department of Imaging ⭐️🧫🧪@DanaFarber
Great opportunity for those with/nearing completion of a STEM undergrad degree who want to expand their research skills in an interdisciplinary setting 🧬
Info/apply: careers.dana-farber.org/job/…
Bing Shui retweeted
Very happy to have started my lab at Stanford @DevBioStanford earlier this month. We will be studying mammalian embryo development, plasticity and resilience. Check out our new website for more details: bowlinglab.org/
Are you looking to explore some cutting-edge cancer research with a group of amazing, motivated, and incredibly fun scientists? Come join us! Please help RT and share to folks who might be interested!
Bing Shui retweeted
Hard launch! First week as a #NewPI @DanaFarber 👩🔬 Interested in molecular imaging, chemistry or radiobiology? Postdoc and research tech positions to follow soon! Eternally grateful to @KevinHaigisLab and the lab for their support over the last 3.5 years 🧬🧫🧪☢️⭐️🔬
Excited to share my PhD work @KevinHaigisLab studying the interplay between oncogenic K-RAS and global miRNA function, out today @MolecularCell ! We found that oncogenic K-RAS suppressed global miRNA function and here is a brief tweetorial: (1/14)
authors.elsevier.com/c/1hM64…
Finally, a special shout out to my PI @KevinHaigisLab for allowing me to dip my toe into this unique and interesting question in KRAS biology that made for an amazing grad school learning experience. (13/14)