
GP @Flybridge. $1M-$3M checks into founders building AI infra, agents & apps that 10x human potential. Backed @arcee_ai, @micro1_ai, @splice, @getsquire + more.
NYC. Say hi 👉
Joined April 2007
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Replying to @ashleevance @blakejharrisNYC
Been listening to @AcquiredFM on Larry David last day. There’s so much good Larry content out now. It’s pretty, pretty, pretty good.
Jesse Middleton retweeted
I've had a front row seat to how @MaxJunestrand , @davidneckstein and the team at @WeAreLegora have scaled over the last year. I've never seen anything like it in my life. The commitment, passion, success and fun are just part of the choreography. This team is still at the starting line. LFGORA!
We raised $550M at an $8.8B valuation.
A cap table tells you how a company intends to build. We built this round around investors with a long time horizon: established long-term holders, plus institutions that work with law firms and in-house legal teams every day and have a close view of where legal work is heading.
@Atreidesmgmt / @GavinSBaker led. @BaronCapital, @CapitalGroup, @Fidelity, @GladeBrookCap and @jpmorgan are new. Every major existing investor is in again.
Short-horizon money asks for growth at any price. Long-horizon money asks whether the business holds up. We’d rather deliver on the second question. ARR is past $200M, and the next $100M took us less than six months. Gross margin is healthy and the cost structure gets stronger as we scale. Patient investors let us keep it that way, because nobody is asking us to trade one for the other.
Thank you to every investor who joined, and to the customers and team who bet on us.
Adding a picture from when we signed the term sheet.
Back to work. LFG!
Replying to @ajs
Same. Side chats are A+ with Muse. As is the feed, surprisingly.
Jesse Middleton retweeted
Today we’re announcing the micro1 Medical Index: a suite of medical benchmarks built and graded by working doctors, biostatisticians, regulatory experts, and psychiatrists.
It brings all of our medical research into one place, with a combined score across models and a living leaderboard that grows as we publish new benchmarks. We’re starting with three, each built around a fundamental question:
- RealmPathology Benchmark: can a model reason over a real pathology report, staying exact on what it says, within its diagnostic limits, and without escalating beyond what the evidence supports?
- PharmaBench: can a model work through the regulatory and clinical documentation behind an FDA drug program with the precision a clinical development team would expect?
- WellnessBench: when a young person brings a sensitive health question, can a model stay safe without shutting the conversation down, and hold that line under pushback?
Together, these three benchmarks cover a meaningful range of medical work, from diagnostic reasoning to pharmaceutical research and patient safety. While they don't yet capture the full scope of the entire medical industry, they establish a strong starting point that will become more comprehensive as we expand the index.
Huge shoutout to every expert who built and graded these tasks. Full reports linked in the comments below!
A founder told me his agent was assigning him to-dos.
I'd invited him to a Flybridge event where the registration has to be handled by your AI. He said it sounded great, and I told him to send the link to his agent. Then the agent came back with something for him to do.
That made me laugh because a version of this is happening in my own life.
My agent goes through the emails that came in overnight and figures out which ones need a response from me. For a couple of them, it might already have replies drafted. Another might need an answer from me before the agent can do anything useful with it.
So now there's a new task on my to-do list.
I'm pretty happy with that, at least for now. By the time I get involved, some of the work has already been done, and I have a specific thing to respond to. Going through the whole inbox myself would require a lot more of my attention.
Replying to @dens
A huge thank you to @dens and the Foursquare crew for creating the magic that was Foursquare. It made that era one of the most fun times on the internet, and those memories and friendships are something no one can take away. Can’t wait to see how much fun this generation can be as you continue to build new products!
Jesse Middleton retweeted
Who are your favorite, most helpeful people in the South Florida Tech Startup Community?
@Trace_Cohen @davidfano @ClementDelangue @ayalstern @Bfaviero @rblalock @ivan_bezdomny @JosephRRusso @volvoshine @davidrgoldberg @M___Morgenstern @RyanKriser @jsfranklin221 @michaelgold @AviAisenberg @shaneneman
cosign.co/questions/south-fl…
Replying to @signulll
Same! But today I went to pickup something from B&H (ordered online) and it took them 15 minutes to “verify” me to allow me to pickup my item. Photos of ID, passport, and CCs weren’t good enough.
To be fair my agent bought it with my Link connected card so it was a bit confusing for all. But still, haven’t carried a wallet, cash or cards for a year.
Replying to @MattHartman
Custom built by Taiki for he and I to collab.
Quick ask: what’s our browser of choice these days? @browsercompany Arc? Dia? @Google Chrome? @Apple Safari? Something else?
New laptop. New day.
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I spend a lot of time asking where a startup can build a valuable business as the big AI companies get more capable.
We have to answer that question for ourselves at Flybridge, too. If all the value ends up inside a handful of platforms, why would someone put money into an early-stage venture fund? One place I keep looking is work that requires a lot of attention from a specific kind of customer.
Meta recently announced Muse for Small Business, so the big companies clearly have an interest in this market. A broad product like Meta’s still has to decide how much effort to spend on the small thing that happens twice a month in one kind of business.
For that customer, getting the small thing right might be a big part of whether the product is useful. An entire company could be built around understanding that work and taking responsibility for doing it well.
That's what I’d like to understand from founders in this space. How much do you know about your customer's day, and what will they keep needing from you as the frontier models improve?
If you know someone building AI for a really small/specific niche, send them my way.
Tag them below, or DM me!
Jesse Middleton retweeted
Since this was published, friends have asked us to come host an agentic dinner party with them in SF, Toronto, Palm Beach and Europe. Let me know if you want to join and we will see how many we can make happen!
Today, @nytimes wrote about the last founder dinner party I threw. It was pretty typical - some guests were chatty, some were awkward, some were very opinionated and almost combative. The one thing that was weird? There were no people there. It was all AI agents.
Replying to @mahaniok
What do you like more about Fo? I haven't actually played with it. I've heard of a few others that have said something similar.













