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ALT https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2023.1065812/full Psychiatry, 16 February 2023 Therapies for obsessive-compulsive disorder: Current state of the art and perspectives for approaching treatment-resistant patients 2. 1st-line treatment Cognitive Behavioral Therapy (CBT) with exposure & response prevention (E/RP) is one of the first-line evidence-based treatments for OCD...several meta-analyses have found a significant reduction of OCD symptoms after a psychotherapy including E/RP, with 42-52% of patients achieving symptom remission ...results should be interpreted considering potential biases, such as the exclusion from the CBT trials of patients with comorbidities or the most severe cases of OCD 3. 2nd-line treatment Taking for granted the heterogeneity in the definition of response criteria in the literature, a recent review on pharmacotherapeutic strategies in OCD suggests that only up to 50% of patients respond to SSRIs

ALT https://www.sciencedirect.com/science/article/pii/S0010440X22000487#bb0595 Science Direct Comprehensive Psychiatry Volume 118, October 2022, 152342 The global assessment of OCD A recent meta-analysis confirmed the previous observation: at least one in ten patients with OCD attempts suicide during their lifetime, while nearly half of individuals with OCD have suicidal ideation.




















