Tim Frost retweeted
“Only those are fit to live who do not fear to die; and none are fit to die who have shrunk from the joy of life and the duty of life.” ~ TR (from his island in DC)
Clinical AI shouldn’t be held to a standard of perfection that human healthcare has never achieved.
Better care. Faster access. Lower costs.
Unleash clinical AI.
CMS just released a new roadmap for clinical AI! It's great to see an administration that is more excited about the potential good for patients and programs than the risks of harm.
There are a few details within that suggest aspects of future regulation (working in conjunction with FDA and with states) as well as suggestion of what services will be reimbursed by new models (beyond ACCESS / chronic disease).
More to come, for now check out the PDF here:
cms.gov/files/document/clini…
→ Start every regulation at zero.
→ Make every rule justify its existence.
→ Repeal outdated rulemaking delegations.
Zero-based regulation. This is the way.
In the six months following the U.S. Supreme Court’s Loper ruling, which decisively overturned the longstanding Chevron doctrine, federal courts invalidated nearly 84 PERCENT of new rules under review.
Agencies can no longer rely on expansive statutory interpretations to justify ambitious regulatory agendas.
Our @DocTFrost shows state agencies how to respond: repeal obsolete statutes, review every rule from zero, and move durable policy into statute.
ciceroinstitute.org/research…
Advanced manufacturing + autonomous production + power abundance is the solution
Great read on the overly-efficient generic drug marketplace in the U.S. and our over-reliance on international sourcing.
Thanks to @washingtonpost for leaning on our data to show pharmacy acquisition cost erosion over time.
wpintelligence.washingtonpos…
3
55
Tim Frost retweeted
Never, ever let them tell you it can't be done.
Palmer Luckey says analysts claiming it's too expensive to manufacture in the US are lying to protect megacorps
"I think I have a more realistic view than almost anybody. One of the problems with all these analysts that are telling you that it's going to cost $37,000 to build an American iPhone or $100,000 to buy an American computer."
"They're trying to prop up a status quo that the megacorporations want to keep going. They want to outsource everything. They want to hire cheaper non-American labor."
"They are willing to say and do anything to convince you that it can't be fixed, that it can't come back, that America is this helpless, neutered, post-relevant empire, and it is just not the case."
"How do I know that? Because I have to make stuff in America every day because I work in the defense industry. The stuff that Anduril makes every day is not actually that different from a computer. My drones are basically computers. They have memory, a GPU, a CPU, sensors, batteries, a rugged integration."
"The only difference between an Anduril attack drone and a laptop is a keyboard and a screen. That is not that hard to figure out, especially for a guy like me who started Oculus and comes from the consumer electronics space."
"We're not going to let people lie about what America can and can't do anymore. We're just going to do it."
In recognition of American Pharmacists Month, HHS leaders @ADM_Christine , @ACF_Adams & RADM Kelly Battese joined @usphscc pharmacy officers to discuss pharmacy priorities, including the benefits of standard-of-care regulatory models that help expand access and improve health outcomes for the American people.
Tim Frost retweeted
We will enter an age of abundance
If we can stop the communists for the next 5 years
Tim Frost retweeted
Alexander Hamilton fought anti-automation and pro-import arguments in the 1700s that hardly differ from the modern day.
Tim Frost retweeted
for those who don’t understand
1) the sandbox allows companies (including ours) to test AI care in production with real patients
2) this allows us to generate massive real world data about safety, quality, and outcomes
3) this paves a way for AI to be a real deflationary force in the country and give people what they want most: cheap, personalized, instant care
Tim Frost retweeted
Utah unveiled 3 new AI sandbox participants this AM:
1) Nolla Health, using face photos for acne Rx's
2) August AI, another refills app
3) Expect Fitness, pelvic floor physical therapy
FDA's discussion paper on generative AI-enabled medical devices gives some indication of their thinking. But there's still ambiguity in how FDA will interface with and learn from Utah and other state sandboxes as they get set up.
Even if states allow AI to prescribe the feds / FDA still have statutory authority over this area and all the sandboxes live (or die) by their grace.
Tim Frost retweeted
I reread this every year.
I cry like a baby every year.
Todd Beamer died a father, husband, and hero.
Todd: Hello… Operator… listen to me. I can’t speak very loud. This is an emergency. I’m a passenger on a United flight to San Francisco. Our plane has been hijacked.
Lisa: I understand. Can they see you?
Todd: No. There are three that we know of. They have knives — razor knives, like box cutters. Someone announced from the cockpit there was a bomb. It sounded fake.
Lisa: Your name?Todd: Todd Beamer. United Flight 93.Todd: They killed one passenger in first class. They forced most of us back. Fourteen of us here. Five flight attendants. The guy with the bomb ordered us to sit on the floor.
Lisa: Are you okay?
Todd: We’re going down… wait. No. We’re leveling off. We changed directions. We’re flying east again.
Todd: A guy named Jeremy called his wife. She told him two planes hit the World Trade Center. Lisa, is that true?
Lisa: I have to tell you the truth. It’s very bad. Both towers are gone. A third plane hit the Pentagon. Our country is under attack. I’m afraid your plane may be part of their plan.
Todd: Oh God. Lisa, will you do something for me? Call my wife and my kids. Promise me you’ll call.
Lisa: I promise.
Todd: Our home number is… You have the same name as my wife. Lisa. We’ve been married ten years. She’s pregnant with our third child. Tell her I love her. I’ll always love her. We have two boys — David, he’s 3, and Andrew, he’s 1. Tell them their daddy loves them and he is so proud of them. The baby is due January 12th. I saw an ultrasound. We still don’t know if it’s a girl or a boy.
Lisa: I’ll tell them. I promise, Todd.(Lisa patches in the FBI.)
Agent: Todd, your plane is on a course for Washington. Best guess is the White House or the Capitol.
Todd: I understand. I’ll be back.
Todd: Everyone knows this isn’t a normal hijacking. We have decided we will not be pawns in their plot.
Lisa: What are you going to do?
Todd: Four of us are going to rush the one with the bomb. Then the cockpit. A stewardess is getting boiling water. We’ll take them out.
Todd: Would you pray with me?They pray the Lord’s Prayer. Then: Yea, though I walk through the valley of the shadow of death, I will fear no evil, for thou art with me.
Todd: God help me. Jesus help me.Are you guys ready? Let’s Roll.
Tim Frost retweeted
i regret to inform you there's absolutely no need to go visit china to see how they manufacture. we know what has to be done. if you want to solve this problem in america, either write a check, build a factory, or get out of the way. thank you for your attention to this matter.
Tim Frost retweeted
I generally avoid legacy media, but both NYT & WaPo had articles about me and our policy org @InstituteCicero this morning.
Although it ignores the bulk of my @8vc work in AI et al, most of the battles to fix healthcare, and takes some license, the WaPo profile was well-written.
Tim Frost retweeted
This morning, both The New York Times and The Washington Post published major stories about @InstituteCicero's impact on public policy and the courage and vision of our founder @JTLonsdale.
Tim Frost retweeted
As of today, Western Chemicals is a proud Texas landowner. Breaking ground at our Houston County ethanol plant before end of August!
Tim Frost retweeted
FDA just published a discussion paper on the regulation of clinical AI. It is directionally good. This is huge news and very exciting!
First and most importantly they propose a framework that emphasizes premarket evaluation for COMPETENCY (not necessarily e.g. clinical results, which would require expensive trials and take much longer to execute), followed by robust post market monitoring.
Some elements of the proposed competency framework are below:
Tim Frost retweeted
Replying to @bryan_johnson
Your instinct is good. We are built with a desire to live forever. Because some part of us understands that we were created to live forever. And we all WILL live forever. The question is whether it will be an eternity of supreme satisfaction or torment.
And the only way to get the kind of eternity that one would want is through the sacrificed blood of Christ on the cross. Saying a prayer now you find this!
Tim Frost retweeted
Almost a year ago, I was driving through the Idaho desert near INL when it finally clicked.
America is attempting to do something never done before: restart an entire industry.
For more than thirty years, we largely stopped building nuclear reactors. But, while most people weren't paying attention, a new generation quietly prepared for the day that might change.
Then came May 2025.
President Trump signed four executive orders designed to accelerate American nuclear. One of them set an extraordinary goal for three advanced reactor companies to go critical by July 4, 2026.
Almost overnight, what had been simmering became a race.
I found myself with a front-row seat.
I realized I had something few people have… access. And with that access came a responsibility to document this story as it unfolds.
Over the past eight months, our documentary crew has gone inside laboratories, construction sites, control rooms, government offices, and startup headquarters.
We watched brilliant people wrestle with impossible engineering problems, politics, tight deadlines and tons of uncertainty.
At first I thought we were making a documentary about nuclear, but I was wrong.
Nuclear is just the lens. The real story is something much bigger. It's about whether America can still build big things.
It's about people willing to devote years of their lives to projects they might never see through.
Today, we're releasing a sneak peek into what will become The Last Renaissance.
This is where it begins. Whether this nuclear renaissance succeeds or fails, historians will look back on this moment.
Over the coming months and years, we'll continue giving you glimpses from inside this journey, bringing you along as one of the most ambitious industrial revivals in modern American history unfolds in real time.
And when it all comes together, it will become a feature-length documentary. For now, we're still in it.
History almost never feels historic while you're living through it. This time, we're making sure no side of the story goes untold.
President Donald J. Trump is reigniting America’s nuclear power production. 🇺🇸
@SecretaryWright launched a pilot for advanced reactors with a mission to start at least three safely by July 4th.
Today, POTUS announced four companies delivered, marking a HUGE SUCCESS. ✅
Tim Frost retweeted
Good morning, I’m waiting for a box of gear to be delivered to me again, so here’s the story of maybe the greatest act of private philanthropy for American public lands in our history: the creation of Grand Teton National Park.
John D. Rockefeller purchased this land for us under the Snake River Land Company quietly buying up about 35,000 acres because he didn’t like seeing development creeping into the valley and he know Grand Teton for what it was-an otherworldly place that needed to be protected for all Americans.
Locals protested an outsider buying up all this land, Congress tried to abolish the early National Monument created by FDR, but the standoff (culminating in a protest cattle drive across the monument) ended when Rockefeller’s land was merged into the modern park. Compromises were struck with locals to enable traditional ranching livelihoods. One of the few national parks in America where you can hunt elk, one of the places where we came up with the idea for the 1964 Wilderness Act (famous meeting at Murie Ranch)
Tim Frost retweeted
SECRETARY RUBIO: This is a distinctive and unique evil. It has always been driven by a hatred, above all else, for civilization itself.
It is a revolt of the worst against the best; of the weak and the cowardly against the strong and the good. It is perpetrated by those who cannot build, cannot create, cannot achieve great things - and take their revenge upon the world for their own inadequacy by seeking to destroy those who can.
This is what radical leftism is. It may wear various different slogans and ideologies across place and time - anti-capitalist, anti-imperialist, communist, anarchist, Marxist - but the fundamental character is always the same.
It is a poisonous resentment cloaked in the language of equality, justice, liberation; an overwhelming need to tear down what greater men have built, to wreck what is beautiful and right, on behalf of people who are only filled with ugliness, and have nothing else to offer the world.
Through violence and terror, they once again seek to impose their ugliness on all of us. The old dogma was wrong. None of this is driven by "idealism." It is not "utopian" - quite the opposite, in fact.
One of the criticisms you sometimes hear of communism is: "It sounds good in theory, but it never works in practice." But that's not true. It doesn't sound good in theory.
The world it envisions for all of us is small, flat and gray - leveled of all exception, drained of all that is good and noble in the human soul. It is a world without courage, creativity, or ambition; without heroes or glory or great causes to strive towards. Without miracles.
Without myths. Without men who rise above the rest to do incredible and extraordinary things. Without God.
For these architects of revolutionary violence, the towering achievements of our civilization are an unbearable humiliation - a reminder of what they cannot do or be.
So they choose to destroy. They attack pipelines, railroads, laboratories, power grids: the physical, embodied symbols of power, invention and achievement.
































