@HouseleyLab

We study molecular mechanisms of genetic and epigenetic adaptation. @BabrahamInst, Cambridge, UK. Main funding @wellcometrust and @BBSRC. Views are our own.

 Cambridge, England
babraham.ac.uk/our-research/epigenetics/jon-houseley
Joined October 2018
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  • Followers581
89Media
We were delighted to welcome five new PhD students this October, joining the Houseley, Richard, Christophorou and Voigt labs #12DaysOfBabraham
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We are excited to have our discovery of Tissue-specific Protection against Protein Aggregation published in #PLOSBiology! #ProteinQC in #Celegans plos.io/44QeDdD

A safety mechanism enables tissue-specific resistance to protein aggregation during aging in C....

This study shows that during failure of core protein quality control in C. elegans, a specialized anti-aggregation mechanism relying on intracellular pathogen response factors and lysosomal mediated...

journals.plos.org
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The @BabrahamInst is looking for individuals to join its Board of Trustees to replace those stepping down during 2023-24 and help shape the Institute's future. Appointments would be for an initial term of three years. Full details: ow.ly/LNIF50M0L4S
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Last few days to apply for a postdoc in our lab on #Celegans & #Aging 👇.
delladavid-lab.bsky.social@DellaDavid_Lab4 May 2022
We have two postdoc positions available! If you want to work with the amazing #Celegans and discover fascinating mechanisms controlling #Aging and #Protein #Aggregation, apply by 19th May at: bit.ly/3sbnSot | bit.ly/39CZTbe Please RT. #proteostasis #postdocjobs
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Join us IN PERSON/ONLINE for a @Uni_of_Essex @EssexLifeSci Seminar on Thursday 1pm GMT! Dr Jon Houseley @HouseleyLab @BabrahamInst will talk about his evolutionary approach to #ageing research--& I hope rep forks In STEM 3.1 or Zoom ID 92545610277 @ResearchEssex #EssexSeminars
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A #researchassistant position is available in our lab at the @BabrahamInst in Cambridge, UK. Requirements: Curiosity, collegiality, commitment and a good grounding in cell culture. We'll teach you everything else! #sciencejobs #stemcells #citrullination #signalling #epigenetics
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We are thrilled to announce that in partnership with @BabrahamUK we have secured funding from @BBSRC to host 15 Collaborative Training Partnerships (CTP) with the first 5 PhD students starting in October 2022! Read more: ow.ly/bmFw50GnAl2
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Excited to share our latest work @NatureComms on how the gene regulatory landscape changes when human naïve pluripotent stem cells transition to a primed state: nature.com/articles/s41467-0… 1/9

Widespread reorganisation of pluripotent factor binding and gene regulatory interactions between...

Nature Communications - The role of transcriptional enhancers and 3D chromatin organisation in coordinating the transition from naive to primed pluripotency remains poorly understood. Here the...

nature.com
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** Job alert ** We are recruiting for a #postdoc position @BabrahamInst to investigate #epigenetic regulation of human pluripotent #stemcells and reprogramming. Please RT! For more info, please see: babrahaminstitute.livevacanc…
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** Job alert ** We are recruiting two #postdoc positions to investigate #epigenetic regulation of naïve pluripotent #stemcells and also of lineage specification in human preimplantation embryos together with @ReikLab and @LabGavin. Please RT! babraham.ac.uk/vacancies-tra…
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Very excited to share our new preprint “The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle” biorxiv.org/content/10.1101/… Thanks to Masami Ando-Kuri, @RodrigoArzt @jorgmorf @jonathancairns @Peter_Fraser1 and all other authors! @IFC_UNAM

The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle

Circadian gene expression is essential for organisms to adjust cellular responses and anticipate daily changes in the environment. In addition to its physiological importance, the clock circuit...

biorxiv.org
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We are seeking an enthusiastic research assistant with a strong background in mammalian #CellBiology and cell #imaging to develop new methods for imaging protein #citrullination in cells. Details here: babrahaminstitute.livevacanc…… Interested? Please get in touch and/or RT!
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Happy to share our latest work: BIR in human cells can also take place at double-ended DSBs, especially in transcribed loci when RNA:DNA hybrids removal is impaired. And this depends on BLM biorxiv.org/content/10.1101/…
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Houseley Lab retweeted
Reik Lab@ReikLab17 Feb 2020
Together with @RuggGunnLab & @LabGavin @BabrahamInst we are seeking a #postdoc to investigate #epigenetic regulation of lineage specification in human preimplantation embryos using #singlecell technologies as part of the @wellcometrust HDBI initiative. Please RT! @IHEC_Epigenomes
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Excellent opportunity for experienced postdoc/senior postdoc to join @annecorcoran11 lab @BabrahamInst Gene regulation in B lymphocyte development #immunology #epigenetics #antibodyrepertoire #ageing #NGS #genome Apply by 20 Jan DM or email for more info babrahaminstitute.livevacanc…
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The upcoming @scilifelab seminar is by Jon Houseley @HouseleyLab from @BabrahamInst Cambridge, UK: 'How random are adaptive genome rearrangements?' December 3 at 15:00, hosted by Ryan Hull @pelechanolab
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9.4 million eligible people not yet registered to vote in #GE2019. Ask everyone you know if they've registered and if not they can use this link: gov.uk/register-to-vote. Tomorrow is the deadline. #RegisterToVote
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We are now 3⃣ days away from the registration deadline. Be heard. Register to vote now: yesiwill.vote/
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The @SamantLab are looking for a postdoc to join the group to study cellular protein clearance mechanisms, utilising #proteomics & #imaging. Apply by Friday 22 November 2019. Full details: ow.ly/rV3L50x7PcK #sciencejobs
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Houseley Lab retweeted
Adrian Liston@LabListon24 Oct 2019
Looking for the first #PhD student to join our lab since the move to #Cambridge! A top project awaits. Yes - this opportunity is for you, please apply! 👩‍🔬🐁🧬🔬🧫 #immunology @britsocimm
Babraham Institute@BabrahamInst21 Oct 2019
Looking for a #lifesciences #PhD? You could follow in the steps of our newest PhD students. Check here for project details: ow.ly/dBvX50wOHEc Projects with @SamantLab @Sharpe_Lab @LabListon
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