JCP keeps clinician-scientists and trainees up-to-date on the latest clinical developments in psychopharmacologic agents. Our podcast: https://xitter.cf/t.co/iXWmMM85rV

Lippincott Williams & Wilkins
Joined January 2011
Dr. Kolodny's guest editorial is available ahead-of-print on our website: 🔗 ovid.com/jnls/psychopharmaco…
Kratom is often described as a botanical substance with opioid-like effects, but @andrewkolodny argues that framing downplays what clinicians are increasingly seeing in practice. @JCPjournal medpagetoday.com/psychiatry/…
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❓Have a psychopharmacology-related question? Consider submitting it to the "Ask the Experts" section in @JCPjournal which provides a forum for presenting questions to psychopharmacology experts. Please email your questions to our Editorial Office at [email protected].
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What do we know about #cariprazine during #breastfeeding? Analysis of milk samples from 5 lactating women found low infant exposure, though reports of infant lethargy and concerns about metabolite accumulation warrant further study. 🔗Read more in JCP: ovid.com/jnls/psychopharmaco…
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Do #pharmacogenomic tests improve patient-centered outcomes in #depression? This study found similar improvements in well-being and symptoms over 12 months regardless of whether clinicians had access to combinatorial pharmacogenomic testing results. 🔗 ovid.com/jnls/psychopharmaco…
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Psychopharmacology is more than matching diagnoses to guidelines. RCTs and guidelines inform treatment, but they do not replace clinical judgment. Our podcast discussion of a new editorial focuses on this topic. 🎧 jcpjournal.libsyn.com/interm… 🧾 ovid.com/jnls/psychopharmaco…
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GLP-1s and lithium: what could go wrong? In a new report from @MayoClinic, the authors discuss a case of severe #lithium toxicity requiring hemodialysis after #tirzepatide initiation in a patient with bipolar I disorder. 🎧 jcpjournal.libsyn.com/tirzep… 📰 ovid.com/jnls/psychopharmaco…
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New pharmacovigilance data suggest that #olanzapine and #clozapine may be more strongly associated with pulmonary embolism than other antipsychotics. Whether this reflects medication effects, underlying severe mental illness, or both remains unclear. 🔗 ovid.com/jnls/psychopharmaco…
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The Journal of Clinical Psychopharmacology is building a presence on @Bluesky, and we’d love for our @X community to be part of it. Follow us on Bluesky Social for early updates, featured research, and insight into psychopharmacology trends. 📲 psychopharm.bsky.social
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Could psychiatry be looking beyond #neurons? A new review argues that #astrocytes and neuron-glia networks may play a central role in mental illness and discusses how findings from #GLP-1 therapies challenge traditional neurotransmitter-based models. 🔗 ovid.com/jnls/psychopharmaco…
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For patients with treatment-resistant #schizophrenia who refuse oral clozapine, intramuscular #clozapine may provide a bridge to treatment. A systematic review found successful transitions to oral therapy were commonly achieved within days. 🔗 Read more: ovid.com/jnls/psychopharmaco…
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Can boosting #serotonin #synthesis improve outcomes when SSRIs are not enough? Our latest review and podcast explore five decades of evidence for serotonin synthesis amplification as an #augmentation strategy. 🎧Podcast: jcpjournal.libsyn.com/seroto… 📜Article: journals.lww.com/psychopharm…
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Obsessive-compulsive symptoms are common and difficult to treat in #bipolar disorder. A new RCT found that adjunctive #memantine significantly reduced #OCD symptom severity, supporting further study of #glutamatergic approaches in BD-OCD. 🔗Read more: ovid.com/jnls/psychopharmaco…
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Toward #precision #psychiatry: In older adults with depression, lower venlafaxine metabolite exposure and lack of early response predicted poor outcomes, but biomarker-informed models performed similarly to clinical predictors alone. 🔗 Read more in JCP: ovid.com/jnls/psychopharmaco…
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What do we know about #cariprazine during #breastfeeding? Analysis of milk samples from 5 lactating women found low infant exposure, though reports of infant lethargy and concerns about metabolite accumulation warrant further study. 🔗Read more in JCP: ovid.com/jnls/psychopharmaco…
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High-dose #propranolol is sometimes used to treat severe aggression and self-injurious behavior in #autism spectrum disorders. In a retrospective review of 52 patients receiving up to 1200 mg/day, no serious cardiologic adverse events were observed. 🔗 ovid.com/jnls/psychopharmaco…
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A reminder that #serotonin syndrome can masquerade as delirium in older adults. This case highlights the dangers of serotonergic #polypharmacy and the importance of coordinated prescribing across specialties. Read more in JCP: 🔗 ovid.com/jnls/psychopharmaco…
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Can #cognition improve during routine treatment for #bipolar I disorder? A prospective cohort study found significant gains in both self-reported and objectively measured cognition over 3-4 months, regardless of medication regimen. Read more in JCP: 🔗 ovid.com/jnls/psychopharmaco…
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Journal of Clinical Psychopharmacology retweeted
Pleased to share our new systematic review and meta-analysis, published in the Journal of Clinical Psychopharmacology, on alpha-lipoic acid as an adjunctive therapy for schizophrenia. pubmed.ncbi.nlm.nih.gov/4253… Grateful to all co-authors for their rigorous and thoughtful collaboration. @JCPjournal
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Can boosting #serotonin #synthesis improve outcomes when SSRIs are not enough? Our latest review and podcast explore five decades of evidence for serotonin synthesis amplification as an #augmentation strategy. 🎧Podcast: jcpjournal.libsyn.com/seroto… 📰Article: journals.lww.com/psychopharm…
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