Pancreatic cancer researcher at University of Pennsylvania. Mommy. Working to make lives better for patients.
Joined October 2020
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Kim Reiss Binder (Kim Reiss) retweeted
Pancreatic cancer is entering a new era of targeted treatment.
In this Gut Onc Lab episode, Dr. Kim Reiss (@KReissMD) joins Dr. Nicholas Hornstein (@GIMedOnc), Dr. Timothy Brown (@TimothyJBrownMD) , and Dr. Udhayvir Grewal (@UGrewalMD) to highlight why 2026 feels like a turning point for PDAC, with growing momentum around BRCA/PALB2-directed strategies, PARP maintenance, and the next wave of RAS-targeted therapies.
🎧 Watch the full Gut Onc Lab episode on OncoNexus:
oncologynexus.com/podcast/ta…
#PancreaticCancer #GIOncology #PDAC #PrecisionMedicine #BRCA #PALB2 #KRAS #TargetedTherapy #Oncology #OncoNexus
Kim Reiss Binder (Kim Reiss) retweeted
New drugs on horizon #PDAC #ESMOGI26
➡️we can go beyond RAS! Profiling for all! inspiring overview @EileenMOReilly
➡️novel approaches TP53
➡️the Claudin 18.2 story builds- bispecifics; ADCs
➡️HRD nb long term rucaparib data
➡️MTAP loss & PRMT5i(nb RASi)
@myESMO @OncoAlert
Probably the most emotional moment to date for our pancreatic cancer community. An enormous, unequivocal win that opens the door to a brighter future. It starts now. ☄️🌟🤩
Kim Reiss Binder (Kim Reiss) retweeted
Rapid oral section- Gastric&HPB. Selfie of chairs and presenters! #ASCO26. #BTC. @KReissMD @GIcancerDoc
Kim Reiss Binder (Kim Reiss) retweeted
SWOG S2001:maintenance olaparib/pembro v olaparib gBRCA1/2 #PDAC
➡️closed due to futility
➡️n = 73 mPFS 8.2 v6.4mths
➡️mOS 20 v 22.1mths
Higher ORR but need understand TiME HRD-PDAC better for better combo! #ASCO26
@ASCO @OncoAlert @pancanireland @KReissMD
Kim Reiss Binder (Kim Reiss) retweeted
Updates ph1 INCB161734 KRAS G12Di
#PDAC #GI26
➡️ sel On/Off, n=61 mono (1200mg) n=44 combo
➡️ORR mono 37% (n=41)
➡️ ctDNA 66% on 1200mg molecular response (≥90% reduction)
➡️ tolerated with GnP and mFFX (data on n=23)
➡️ KRAS CN - ‼️resistance
@ASCO @myESMO @OncoAlert
🚨 We have two ongoing maintenance trials for patients with pancreatic cancer and at least stable disease after 4-6mo of chemo. FFX or G/A, mPDAC or LAPC. If your patient needs a chemo break, send me a DM! @PennMedicine
Kim Reiss Binder (Kim Reiss) retweeted
After being diagnosed with #PancreaticCancer, Steven Merlin found hope through a #clinicaltrial. Now as an @eaonc advocate, he shares his perspective on the benefits of clinical trials. Read his inspiring story: bit.ly/beatingtheoddsf25 cc: @letswinpc, @PanCAN, @SeenaMagowitz
Hazel the Chicken Gets Eggstra Help is officially on the shelves at two of our local bookstores! @MainPoint_Books and Character Development! Thanks to everyone who has supported - we really hope this book will make a positive impact on kids. #kidlit
Kim Reiss Binder (Kim Reiss) retweeted
Do you have #PancreaticCancer with a BRCA1, BRCA2, or PALB2 mutation and resected (surgically removed) pancreatic cancer? If so, you may be able to participate in this study of a potential new treatment. Learn more: bit.ly/apollo-trial cc: @KReissMD
Kim Reiss Binder (Kim Reiss) retweeted
You may be eligible to participate in a #PancreaticCancer study, EA2192/APOLLO, for patients with #PancreaticCancer that has been surgically removed and has a BRCA1, BRCA2, or PALB2 mutation. Learn more: bit.ly/apollo-trial #pancsm cc: @KReissMD
Kim Reiss Binder (Kim Reiss) retweeted
Learn about the EA2192/APOLLO study, treating patients with #PancreaticCancer that has been surgically removed and has a BRCA1, BRCA2, or PALB2 mutation. More information: bit.ly/apollo-trial #pancsm #pancaware cc: @KReissMD
Kim Reiss Binder (Kim Reiss) retweeted
Congrats to the authors. The impact is high. Aspirin 160mg daily for CRC secondary prevention if PI3K (+), the risk becomes half!
Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer
@NEJM
doi.org/10.1056/NEJMdo008154
👉Low-dose aspirin resulted in a significantly lower risk of recurrence w/ hotspot mutations
👉similar benefit w/ other alterations in PI3K pathway
🧐I would take it...
@myESMO
Putting out the 🦇signal for #EA2192 (APOLLO). 97/152 patients enrolled! Pts with BRCA or PALB2 who have completed curative intent tx for PDAC within the last 3mo are eligible. 🎯💊 @eaonc @EileenMOReilly @BasserBRCA @FacingOurRisk @anup_kasi @letswinpc
Kim Reiss Binder (Kim Reiss) retweeted
Revolution Medicines Daraxonrasib data in first line metastatic #PancreaticCancer - monotherapy & combination with Gemcitabine nab-paclitaxel. Even monotherapy ORRs and DCRs are impressive! Do you need the chemo? Grade 3 AEs go from 35% to 58%. RASOLUTE 303 will answer.
Kim Reiss Binder (Kim Reiss) retweeted
Please don't forget. Last day to submit ASCO GI #GI26 abstracts is September 9. Also, senior investigators, please remember the place of honor for you is last author. First author is for people developing their careers.
For every kiddo who has felt a little different in the classroom, @BKaplan12 and I co-wrote this book to help them know it’s ok to need some extra help! Illustrated by Avery Stern. @IngramPubPros @MoWillems #HazeltheChicken #SpEd #speced #childrensbooks
@The_Pigeon would you read this book? You do often seem to need extra help…🤔