We study the ecological, evolutionary, and within-host dynamics of RNA viruses using quantitative approaches. @EmoryUniversity Department of Biology

Atlanta, GA
Joined January 2020
Our paper on influenza reassortment in mammals is out now on @NatureComms! Congratulations to all our collaborators!rdcu.be/cZtAo @anice_lowen @LucasFerreri1 @KoelleLab @CRP_FLU_UGA @Juaco1802 @Aivlys87 @juergenricht @CEIRRNetwork #LoveVirology
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This week's EEB Thurs Seminar features ALUM Dr Katia Koelle @KoelleLab presenting Using genetic data at multiple scales to understand constraints on viral adaptation. 3pm, 1010 Bio Sci Bldg and Zoom live, see poster #eventalanche #Genetics #diseases
congratulations to Dr. @brent_allman on his amazing PhD defense! i've been very lucky to get to co-advise brent with @KoelleLab
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Koelle Lab retweeted
Less than 2 weeks left to apply for our workshop and for talks/posters! eeid-2022-emory.org/registra…
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Check out our latest on flu reassortment from @ketakiganti and a fantastic group of collaborators including @LucasFerreri1 @RajaoPerez_Lab @KoelleLab, Juergen Richt, Wenjun Ma and their groups. #LoveVirology
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Koelle Lab retweeted
Some very exciting news...our website is LIVE!! eeid-2022-emory.org/ #EEID2022
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After a reanalysis of our data, @m_a_martin and @KoelleLab suggested using a higher AF threshold of 6%, which reduced the estimated bottleneck sizes mostly to 1-3 virions. bit.ly/3CsIcof 3/
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Pleased to see our contribution to the discussion on estimating the transmission bottleneck size of SARS-CoV-2 (=how many virions give rise to a new infection) published in @ScienceTM . bit.ly/3blrOtY #SARSCoV2 #COVID-19 #Virology #Pandemic 1/
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A great opportunity @EmoryTMLS to work as an interdisciplinary postdoctoral fellow in the theory and modeling of living systems! apply.interfolio.com/88768
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Replying to @KatherineJWu
My allstars are : @joanneflynn19 (solving TB vaccines) @scienceCC (maternal fetal barriers all star) @SSCLabQuips (all things influenza) Kanta Subbarao @WHOCCFluMelb (emerging pandemic threats) @anice_lowen (flu transmission) @CBLopezLab (DIs and better vaccine platforms)..
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Koelle Lab retweeted
What factors shape evolution of influenza virus within an individual? Happy to share our collaborative work led by @kaaamato with Luis and Kat and @tcflab, @SSCLabQuips, and @KoelleLab that shows genetic bottlenecks restrain intrahost influenza virus evolution. 1/10
Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks biorxiv.org/cgi/content/shor… #bioRxiv
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#ClubEvMed next week with Katia Koelle @KoelleLab! She'll discuss transmission bottlenecks in SARS-CoV-2 and what they mean for transmission tree reconstruction and viral evolution at the population level. Join us next Tuesday 8/24 at 12pm EDT/18:00 CEST! duke.zoom.us/meeting/registe…
Why does a particular pathogen infect some age groups more often than others? And why do different pathogens, some even closely related, have different age distributions of cases? A thread about our new paper published today in @NatureComms 🧵(1/14) go.nature.com/3BdevaL
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We are hiring multiple postdocs at @EmoryTMLS Come work with @dbweissman @gordonberman @sshekhr @Samuel_J_Sober @The_David_J @jenniferrieser @DanielMSussman @nicvega1 @KoelleLab and other great faculty at multiple departments at Emory!
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"Reinfection" has become a scary word, and often seems to hint that our immune defenses are failing us. But that's not the only reason a virus might visit the same person twice, @katherinejwu writes: on.theatln.tc/QG5nP10
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Using domestic cats as a model, @KATarinambraun @GageKMoreno @tcfriedrich and colleagues @UWMadison show that within-host #SARSCoV2 genetic variation is predominantly influenced by genetic drift and purifying selection. buff.ly/2O8SaXB
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I've spent a lot of this past year thinking about the word reinfection. This piece distills some of my thoughts about its meaning, its complexities, and even the nuances of the term itself. 1/ theatlantic.com/science/arch…
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