PhD @likat_rostock, Postdoc @Maes_Group & @RoelfesGroup Now (substitute) professor in organic chemistry @unihh
Hamburg, Germany
Joined May 2017
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- Following466
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Lars Longwitz retweeted
Design and Evolution of an Artificial Friedel–Crafts Alkylation Enzyme Featuring an Organoboronic Acid Residue | Journal of the American Chemical Society @TotalSyntheses #FriedelCrafts #Alkylation #Biocatalysis #Organoboronic pubs.acs.org/doi/10.1021/jac…
Lars Longwitz retweeted
This month, an exciting paper has been published in @Nature from @RoelfesGroup, reporting the design of a boronic acid-integrating #enzyme that allows chiral #organocatalytic reactivity not achievable with natural or chemical catalysts. 1/3
Lars Longwitz retweeted
A newly designed enzyme containing boron shows promising catalytic properties currently not found in nature.
It could lead to applications in fields such as medicine or green chemistry.
In @Nature
Led by @RoelfesGroup @univgroningen with @MXESRF
▶️esrf.fr/home/news/general/co…
ALT Close-up view of an active site showing electron density at 1.72 Å resolution of a cyclic boronate-ester intermediate, obtained with X-ray diffraction data collected at the ESRF MASSIF-1 beamline. The observed intermediate supports the unique catalytic role of the boronic acid group in stereoselectively converting alpha-hydroxyketones to oximes. Credits: A. Thunnissen.
Lars Longwitz retweeted
Boron catalysis in a designer enzyme (@Nature): nature.com/articles/s41586-0… (@RoelfesGroup, @LongLarf, @reubenlg).
Lars Longwitz retweeted
Nature research paper: Boron catalysis in a designer enzyme go.nature.com/4bxKuDT
Lars Longwitz retweeted
🚨🚨🚨 We are hiring! We are looking for 2⃣ PhD students who want to join us @StratinghInst for awesome research in the field of continuous #enzyme #evolution! Informal questions per DM. Click the link below to apply! #MolecularEvolution
Please RT!
rug.nl/about-ug/work-with-us…
Lars Longwitz retweeted
Publishing sucking the joy out of our profession
teapaw.org/SteveStuWill/status/15…
Lars Longwitz retweeted
Hello phosphine my old friend
I've oxidised you once again
(we finally recorded it, turn the sound on if you dare)
Full length song on youtube: youtube.com/watch?v=C446m6rh…
Lars Longwitz retweeted
Lars @Longlarf moved on for a PostDoc at the University of Antwerpen @UAntwerpen working on C–H functionalization in the group of Bert Maes. Good by and good luck! CU
Lars Longwitz retweeted
T. Werner and co-workers use #plasma-assisted immobilization to synthesize supported #organocatalysts for #carbondioxide fixation in the form of cyclic carbonates @unirostock @LeibnizWGL doi.wiley.com/10.1002/cssc.2…
Lars Longwitz retweeted
Reduction of Activated Alkenes by PIII/PV Redox Cycling Catalysis (Werner) doi.wiley.com/10.1002/anie.2…
Lars Longwitz retweeted
Phosphetane Oxides as Redox Cycling Catalysts in the Catalytic Wittig Reaction at Room Temperature ow.ly/7itp50wKPFc
Lars Longwitz retweeted
anti-1,2,2,3,4,4-Hexamethylphosphetane 1-Oxide
Trevor V. Nykaza, Julian C. Cooper, and Alexander T. Radosevich
orgsyn.org/demo.aspx?prep=v9…
Lars Longwitz retweeted
Phosphetane Oxides as Redox Cycling Catalysts in the Catalytic Wittig Reaction at Room Temperature pubs.acs.org/doi/pdf/10.1021…
