Postdoc in Aifantis and Beck Labs @nyulangone | PhD @GSKGradSchool @MSKCancerCenter @PapaemmanuilLab | population and single cell genomics in heme malignancies
New York, NY
Joined January 2020
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Thrilled to see our work out today! It’s been a joy to be a part of this incredible team! 🧬🩸
🎉Excited to present our latest work out today @Nature 1.What gives a leukemia its phenotype – the oncogenic driver or the differentiation stage of the cell-of-origin? 2.Why do RAS mutations always happen late in AML? 3.Who will relapse after VEN? nature.com/articles/s41586-0…
Thank you @CancerResearch Institute for your support throughout my postdoctoral fellowship, highlighting our work, and bringing awareness to MDS and VEXAS! 🧬🩸🔬
#MDSsm #VEXAS @iannisaifantis1 #BeckLab @Perlmutter_CC @nyugrossman #MDSAwarenessDay
Myelodysplastic syndromes (MDS) are rare blood cancers.
On #MDSAwarenessDay, we spotlight CRI Irvington Postdoctoral Fellow @MariaSirenko of @nyugrossman, who studies the link between inflammation and MDS.
Learn more: bit.ly/4ynEjx8
#BloodCancer
Maria Sirenko retweeted
Our multicenter VEXAS study is out in @AJHematology! 66 patients, alloHSCT vs HMA. First comparative dataset. Key points: 100% molecular remission with transplant vs 22% with HMA; OS benefit (HR 0.20, p=0.024). AlloHSCT = potential cure in selected patients.🧵👇#VEXAS #Hematology
Maria Sirenko retweeted
Retrospective study of 135 patients with SSc-ILD showed elevated baseline KL-6 levels and doubling of KL-6 levels at any time over subsequent 6 months were associated with increased risk of progressive pulmonary fibrosis
ACROR
doi.org/10.1002/acr2.90013
ALT Performance of Circulating Inflammatory Biomarkers and Krebs von den Lungen 6 for Predicting Progressive Pulmonary Fibrosis in Patients With Systemic Sclerosis–Associated Interstitial Lung Disease. Graphical abstract created using BioRender
Maria Sirenko retweeted
We're hiring! 🔬 🧬
The Cellular and Tissue Genomics department at Genentech is looking for a Research Scientist (contractor) to join us in building large-scale perturbation datasets using optical pooled screening (OPS/PerturbView).
Maria Sirenko retweeted
The 3rd International VEXAS Workshop is coming to Milan 🇮🇹
📅 Sept 24–25, 2026
📍 San Raffaele Scientific Institute
🔔 Registration & abstract submission opening soon!
Outstanding speakers on VEXAS... and beyond!
Stay tuned and repost! 👀
#VEXAS #Hematology #Rheumatology
Maria Sirenko retweeted
I spoke today with Maria Sirenko from Perlmutter Cancer Center @Perlmutter_CC and NYU Langone Health @nyulangone regarding her interesting #ASH25 #ASH2025 presentation on VEXAS syndrome - here is her summary:
Come by this morning to hear about our work on VEXAS! #ASH25
Looking forward to these great presentations (among many) today at #ASH25 #ASH2025 by @Perlmutter_CC
@nyulangone @NYULH_DeptofMed @nyugrossman
faculty and trainees - Lots happening!
Maria Sirenko retweeted
Looking forward to these great presentations (among many) today at #ASH25 #ASH2025 by @Perlmutter_CC
@nyulangone @NYULH_DeptofMed @nyugrossman
faculty and trainees - Lots happening!
Honored to be part of such a great lineup of #WomenInHematology today!
Our first session comes to conclusion with phenomenal talks by @MariaSirenko on UBA1 mutations in MDS, @ZhuoerXie on MDS diagnostics and therapy, and @DanielleHammo20 on VEXAS syndrome.
The recordings will be posted online for those interested.
#WIH #WomenInHematology
Maria Sirenko retweeted
Our first session comes to conclusion with phenomenal talks by @MariaSirenko on UBA1 mutations in MDS, @ZhuoerXie on MDS diagnostics and therapy, and @DanielleHammo20 on VEXAS syndrome.
The recordings will be posted online for those interested.
#WIH #WomenInHematology
And Dr. Cat. Jamieson opening the first session on myeloid neoplasm with her talk on stem cells and aging in #MPNsm
Tonight we #LightTheNight - the future of blood cancer research is bright! @Perlmutter_CC @nyulangone @BloodCancerUtd
Inspired by last night’s @CancerResearch Institute gala and the amazing community dedicated to advancing cancer research. Honored to be a CRI Fellow! Thank you for your support! ✨
Maria Sirenko retweeted
🚨🚨Paper out! 🚨🚨
Delighted to share our work, now published in @NatureGenet 🧬! shorturl.at/94s5S
We identified a targetable, chromothripsis-associated genetic event in blast phase (BP) MPN, a particularly poor prognostic subtype of acute leukaemia. 1/n
🧵👇
ALT Scientific illustration @ArbachHratch
Delighted to share our study out in @CellStemCell today from the dream team @PapaemmanuilLab @iannisaifantis1 @AkEisfeld @landau_lab!
We profiled IDH-mutated AML patients to define how IDH and co-mutations shape the disease at baseline and responses to IDH-inhibitors.
🧵👇
Please check out the paper @CellStemCell for more: authors.elsevier.com/c/1l8Kj…
We hope this study pushes precision medicine forward and ultimately improves outcomes for AML patients. We share our approaches + data as resources for the community and are eager to collaborate.
#AMLsm