@PfanderLab

Discovery Science in the Genome Integrity field. Opinions are our own.

 Dortmund, Germany
ccb.tu-dortmund.de/en/professorships/dolce-dortmund-life-science-center/pfander/
Joined September 2021
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  • Followers612
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Publication alert! 📰 Great job to @hopfnerlab and collaborators on the new publication in @NatureComms! Read more about it here: nature.com/articles/s41467-0…

Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles

Nature Communications - How DNA glycosylases repair base lesions within nucleosomes remains unclear. Here, the authors determine the cryo-EM structure of 8-oxoguanine-DNA glycosylase 1 bound to an...

nature.com
hopfnerlab@hopfnerlab4 Nov 2024
Check out our latest structural paper about human OGG1 processing DNA lesions within nucleosome core particles, in collaboration with Chuanzheng Zhou's lab. #DNArepair #cryoEM nature.com/articles/s41467-0…

Structural basis for human OGG1 processing 8-oxodGuo within nucleosome core particles

Nature Communications - How DNA glycosylases repair base lesions within nucleosomes remains unclear. Here, the authors determine the cryo-EM structure of 8-oxoguanine-DNA glycosylase 1 bound to an...

nature.com
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We are pleased to inform you that the meeting “From Genome Instability to Cancer: A tribute to Angelos Constantinou” that will take place in Carry-Le-Rouet from March 10th to March 13th 2025 is now open for registration on the link: tribute2angelos.fr/page/home…
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Replying to @RogerRogergr
@RogerRogergr we are really looking forward to your presentation at #DDRCT25 in Lisbon🌞 Registration is OPEN and we have short talk spaces available. 📣Help us spread the word - Please RT to let your followers know! Thank you! Find out more: bit.ly/3BTmZbQ
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📢The deadline is approaching!! This is your last week to apply for exciting projects @IMPRS_LM in the labs of Ralf Erdmann, @kw_kliza, @hemmo_lab, @AndreaMusacchi1, @PfanderLab, Barbara Saccà, Daniel Summerer, Jörg Tatzelt, @BTrappmann, @LabWestermann & @winklhofer_lab
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Congratulations to the best poster prize winners Vanessa Borges-Pires, Anita Jopkiewicz, Jessica Spindler, Maximilian Götz, Na Wei, George Galea of the German Society for DNA repair DGDR meeting 2024 in Cologne @MPIAGE @CGA_age @CECAD_ @UniCologne @spanier55 @PfanderLab
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An intact genetic information is the fundament of life. If you are interested to apply precision genome engineering and state-of-the-art sequencing technology join the @PfanderLab @IMPRS_LM #PhDposition #IMPRS #cellbiology #DNAreplication #genomeengineering
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Replying to @groth_anja @GrundforskFond @cancer_dk
Wishing you all the best for this epic adventure!!
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The lab moved to the Technische Universität Dortmund - exciting times ahead: ccb.tu-dortmund.de/en/profes…

Team - Cordes

List of staff of Prof. Cordes in the Faculty of Chemistry and Chemical Biology at TU Dortmund University

ccb.tu-dortmund.de
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Replying to @GlattSebastian @VetmeduniVienna
Exciting - congrats...
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Pleasure to host the 2024 meeting of the German Society for DNA Repair ⁦@MPIAGE⁩ ⁦@CECAD_⁩ in Cologne with outstanding international guest speakers and the amazing community of DNA repair researchers in Germany with ⁦@spanier55⁩ ⁦⁦@PfanderLab⁩
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Replying to @schumacherbj @MPIAGE @CECAD_
We are absolutely delighted to host you all in Cologne this year and hope you are enjoying the meeting!
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Replying to @CejkaLab @Nature @CeppiIlaria @DelloStritto_MR @PabloHuertasLab @SylvieNoorderm1
Congrats on this fantastic story. Great to see it published!!
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Mechanism of homology search expansion during recombinational DNA break repair in Saccharomyces cerevisiae dlvr.it/TCxvLF
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📢Are you eager to join an international community of scientists to tackle novel and exciting research projects in the areas of #biochemistry, #structuralbiology, #cellbiology, #chemicalbiology and #syntheticbiology? Applications for the @IMPRS_LM #PhDprogram are now OPEN!!!
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CMG helicase disassembly is essential and driven by two pathways in budding yeast Karim Labib and colleagues show that Pif1-family helicases mediate an ancestral pathway for ‘old’ #replisome disassembly during the subsequent S-phase embopress.org/doi/full/10.10…
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PfanderLab retweeted
Cejka Lab@CejkaLab10 Jul 2024
Check out our latest paper showing that HLTF removes Cas9 from DNA, explaining phenotypic differences when using the two Cas9 nickase variants. Important for gene editing! Thanks to @giordano_reg & Rosaria and @MartinJinek @taekjip @nussenza nature.com/articles/s41467-0…

HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing

Nature Communications - Cas9 remains bound to DNA after cleavage and its removal is required for DNA double-strand break repair. Here, the authors show that the HLTF translocase disrupts the Cas9-...

nature.com
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Jim - being a superstar of yeast genetics has to be fantastic. People must ask you for selfies all the time... 😃
Jim Haber@Yeastdoc123 Jun 2024
Who needs a duckboat?
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Replying to @zha_lab @KJArmache
Thank you, social DNAing for the invitation and for providing such a fantastic service to the community.
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Replying to @zha_lab @haicovanattikum
Thank you, social DNAing community for the inivitation - very much looking forward to sharing our new data.
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Grateful for the opportunity to present our work this week, and happy to see three other former graduate students of the late Stefan Jentsch on this list @PfanderLab @RapeLab @stingele_lab. This one is for you, Stefan!
Zha Lab@zha_lab18 May 2024
Where is the spring? Are you ready for the summer? Social DNAing is. Check out our 2024 late spring and summer speakers. The website will be updated soon: cancer.columbia.edu/research…. Thank you for helping us RT.
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