First in the world to perform laparoscopic radical prostatectomy using FlexDex platform. Prior USAF. Urologist in Binghamton, NY and Norfolk, UK. Views my own.

United States
Joined July 2017
Richard Knight retweeted
In a 10-yr follow-up of a randomized trial, Retzius-sparing RARP (better early continence) showed worse long-term cancer control than the anterior approach — 2.64x higher progression risk after adjustment. Post-hoc, hypothesis-generating. free link:authors.elsevier.com/a/1njm6…
5
33
1
112
8,973
First 6.3Fr ureteroscope trial! The picture was phenomenal. The scope went up the ureter with no wires, no access sheath, thus no artifact, which is great for diagnostic purposes. #3.4Fr working channel @NYUHSINC @AmerUrological geyi-medical.com
5
10
1,504
Richard Knight retweeted
PRACTICE CHANGING: #KEYNOTEB15/EV304- in #MIBC, periop EV/P led to sig EFS (NR v 48.5m, 24m EFS 79.4 v 66.2%, HR0.53; 0.41-0.7), OS (NR v NR, 24m estimated OS 86.9 v 81.3%, HR 0.65; 0.48-0.89), pCR  (55.8 v 32.5%) benefit v. neoadj gem/cis, supporting EV/P as SOC in this setting
1
5
1
12
8,459
Richard Knight retweeted
Cochrane updated its PSA screening meta-analysis. 789,086 men across 6 RCTs. ➡️ PCa-specific mortality: rate ratio 0.87 (moderate certainty) ➡️ Metastatic diagnosis: RR 0.65 ➡️ Adverse events / QoL: little to no difference Why this matters: 💡 PSA screening is back on stronger evidentiary footing for disease-specific mortality. Shared decision making still drives the recommendation downstream and additional tools (biomarkers and MRI) continue to improve the gap. bit.ly/CochranePSA2026 @EBMUrology #ProstateCA #Screening #Cochrane #GUonc #AUA26
9
10
1,004
Richard Knight retweeted
PSA nadir at 24 weeks remains one of the strongest prognostic signals mHSPC, but the meaning depends entirely on metastatic volume. ➡️ Pooled analysis of 5 STAMPEDE phase 3 trials (n=7,129) ➡️ With abi±enza + PSA ≤0.2 ng/mL at 24 wks: 96-mo OS was 64% in low-volume mets vs 45% in high-volume ➡️ Non-metastatic, node-positive: 79% 96-mo OS Could PSA nadir + volumetric burden refine clinical-trial enrichment for treatment intensification? 🩺 bit.ly/3PgpID1 #ProstateCA #mHSPC #GUonc
1
31
65
4,374
Richard Knight retweeted
Study examines the path to proficiency in prostate MRI interpretation for trainees. @ddeniffel @TU_Muenchen & @trwherrmann join @zklaassen_md @GACancerCenter to discuss learning benchmarks for prostate MRI interpretation from 14 MRI-naive trainees reading 200 multiparametric MRI cases. #WatchNow > bit.ly/4sPIhww
4
15
1,239
No antibiotics for transperineal prostate biopsy? 🤔 Multi-institutional cohort (n=904): • UTI rate: 2.0% — no difference with vs without antibiotics • Urosepsis: rare (0.2%), only in antibiotic group • AUR: 4.9%, linked to larger prostate size 👉 Antibiotics may not be necessary for TPB Congrats to @MatveyTsivian and Rob Smith for this contribution. 🔗: sciencedirect.com/science/ar… @EMW2000 @MatveyTsivian @JayChavaliMD @JL_Drerup @SES_AUA @UroOnc @SUO_YUO @GenevaMaeP @LuisMedinaMD
2
8
1
18
9,975
Wellness is active, not passive. It's the choices we make today, and every day that shape our health. On this International Wellness Day, what choice will you make?
19
36
5
121
40,996
Richard Knight retweeted
Original Article: Perioperative Enfortumab Vedotin and Pembrolizumab in Bladder Cancer (phase 3 KEYNOTE-905 trial) nejm.org/doi/full/10.1056/NE… Editorial: Enfortumab Vedotin plus Pembrolizumab as Perioperative Therapy nejm.org/doi/full/10.1056/NE… #Oncology
1
54
1
131
24,641
Richard Knight retweeted
Examining guidelines on radiotherapy for #BladderCancer with carcinoma in situ. @ConstanceHuck joins @UroDocAsh to examine whether carcinoma in situ should contraindicate trimodality therapy for muscle-invasive bladder cancer. The conversation highlights how historical data showing poor outcomes with CIS may be outdated, as older studies used split-course radiotherapy and inferior imaging techniques. #WatchNow on UroToday to learn more > bit.ly/4pVb8NA
1
5
17
1,628
🚨ICE/Border Patrol agents were caught on camera committing a hit-and-run in Minneapolis. In the video, an unmarked federal vehicle is stopped in the road. A legal observer is sitting in a car behind them, not violating the law, just observing. Then, without warning, the agents start reversing the vehicle towards the observer… But, they failed to notice a parked car sits directly behind them. As the observer backs up, the federal vehicle slams into the parked car. They stop… and pull forward. You can see the moment they realized they just fucked up, and are debating what to do. They realize no one is in it… so they drive away. And this isn’t the first time… ICE and Border Patrol agents are driving aggressively through communities across the country, using their vehicles as weapons, putting neighbors, families, and bystanders at risk. And anytime they hit someone, instead of a parked car, they aggressively arrest the person they hit and say they were “rammed.” For a department that constantly claims it’s hunting criminals, their agents sure seem to be the ones committing the crimes.
498
6,311
199
16,514
814,772
#BREAKING ICE just shot and killed someone again. In Minneapolis. 5 shots. In front of Glam Doll Donuts
5,224
23,875
3,794
103,064
13,393,350
Richard Knight retweeted
Drop Site obtained harrowing footage of the latest killing which appears to be from the perspective of the woman in pink filming from the sidewalk
5,634
30,014
9,398
108,761
24,101,055
Looking forward to #SGSU26 with this outstanding urologist and friend, Dr. Matthew Kasprenski. @HiltonHotels @LongBeachCity @govurology @whaler170mk
1
65
Countdown to Long Beach for Kimbrough Urological Meeting! All Urologists and Urology Professionals are invited to attend. Program approved for 18.75 CME. see program tinyurl.com/mw3hnf8e #sgsu26
1
1
69
🚨23 years of PSA screening in @NEJM 🚨 👉ERSPC RCT of >162k patients 📅Median 23 year f/u PSA screening lead to... 📉 #prostatecancer mortality by 13% ✅1 death prevented for every 456 men invited for screening or 12 diagnosed w/ PCa 📉Risk of advanced PCa by 34% ⭐️Benefit continues to rise over time as harm-benefit ratio improves 🔗shorturl.at/ajgNN @PCF_Science @PCFnews @urotoday @UrologyTimes @renalandurology @UroOnc
12
78
6
189
106,569
Love is stronger than hate. Love is love. @NYUHSINC
5
487