Senior Scientist @Regeneron • Previously: Hadjantonakis Lab • @sloan_kettering / @WeillCornellGS • #LGM
Joined April 2010
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Vidur Garg retweeted
Excited to share this collaborative work with @Hadhjantonakis and @dana_peer led by @Vid_ur reporting drastically different interconversion efficiencies between ESC and XEN, unique trajectories mimicking in vivo states, and key plasticity barriers. cell.com/developmental-cell/…
🚨 It's finally out!! I'm happy to share our collaborative work from the Hadjantonakis, @efapostolou29 and @dana_peer labs. We wanted to know what makes embryonic/pluripotent cells different from extra-embryonic endoderm cells (1/6)
sciencedirect.com/science/ar…
But how does this inform our understanding of lineage specification in the embryo? Turns out the transcriptional changes we detect in vitro also resemble cell states in vivo during EPI/PrE specification (5/6)
Massive thank you to the dream team from the Tri-I/tri-lab collaboration and all co-authors for their hard work and contributions @SettyM @AlexPPolyzos @djmurph93 (6/6)
Vidur Garg retweeted
Officially out in @NatMetabolism📖: our latest work showing changes how cells acquire amino acids during early development. Congratulations to Pavlina! rdcu.be/du2Z7 @SKI_CellBiology
Vidur Garg retweeted
Super excited to share the final publication of Spectra, fruit of the wonderful collaboration between
@russell_kunes and @science_wallet, a gene program factorization program that I hope will help many interpret and bring insight from their single-cell data -->
Vidur Garg retweeted
Very excited for the first machine learning model from our lab, named 3D-HiChAT developed by @AlexPPolyzos, that enables prediction of 3D complex regulatory relationships, including enhancer hierarchies and 3D hubs that control gene coregulation.
Excited for our latest work biorxiv.org/content/10.1101/… with @efapostolou29 & @artsinyc. We study the role of 3D hubs & enhancer rewiring in early developmental lineages & introduce 3D-HiChAT machine learning approach to nominate impactful enhancers for gene regulation.
Vidur Garg retweeted
Happy to share our new preprint, @efapostolou29 lab! We mapped 3D Enhancer-Promoter connections in mouse TSC, ESC and XEN Cells, and created a machine-learning model, 3D-HiChAT, that uses 1D and 3D features to predict gene expression, validated by CRISPRi. doi.org/10.1101/2023.07.19.5…
Vidur Garg retweeted
Deadline this Friday!
Calling all PhD (or equivalent) students within 2 years of graduation or who have graduated in the last year: Join us for an opportunity to visit with faculty at @FredHutch and hear about career opportunities at this world-renowned institution:fredhutch.org/en/events/prim…
Vidur Garg retweeted
Our latest work on engineering extrachromosomal circular DNAs (ecDNAs) is now available in @biorxiv.
In this preprint we describe a novel strategy to engineer the formation of large (>1 Mb), multigenic, amplifications mediated by ecDNAs in cells and mice.
biorxiv.org/content/10.1101/…
Vidur Garg retweeted
Excited to share initial press release @BlueRockTx on promising results of Phase 1 trial in 12 PD patients bit.ly/3JCKneG. A major milestone on a 20+ year journey. Amazing leadership by @TabarViviane, @MSKCancerCenter & @BlueRockTx (@bigosi, Mark Tomishima & many more).
Data from Ph 1 trial of dopamine neuron grafts in patients with #Parkinsons are very promising: a long standing dream & lots of work;Excited for #Parkinson patients & proud of the team my lab led by JinghuaPiao @studerl lab,@MSKCancerCenter @BlueRockTx
Vidur Garg retweeted
New preprint! We present a pipeline, called scUTRquant, that simultaneously quantifies gene expression and 3′UTRs from scRNA-seq data.
Comprehensive annotation of 3′UTRs from primary cells and their quantification from scRNA-seq data biorxiv.org/content/10.1101/…
Vidur Garg retweeted
Looking forward to presenting our @efapostolou29 latest work at #ISSCR23 regarding Germinal Center B-cell plasticity and stem-like functionality. Please join us on June 15th during the TSC - Epigenetics & Tissue Biology track. What a treat 🎉for my first ever @ISSCR meeting ! 👇🏻
Extremely grateful to have heard Dr. Anthony Fauci speak at #AAI2023
🙌🏽🔬🧪 @ImmunologyAAI
Vidur Garg retweeted
So thrilled to share our work on epithelial cell behaviors in the axial mesoderm. Everything’s coming up roses 🏵️🌹
cell.com/developmental-cell/…
Vidur Garg retweeted
Excited to share our latest review with @cmuyehara @CellReports discussing advances in the ever-changing field of enhancer-promoter interactions with an emphasis on the roles and functions of complex 3D hubs cell.com/cell-reports/fullte…
Vidur Garg retweeted
We are recruiting a research tech with some experience in handling a mouse colony. Location: MSKCC, Manhattan. Competitive pay and benefits. Email: [email protected] if interested. Please RT