Interested in biophysics & neuronal mechanisms of anesthetics. MD, PhD from @RockefellerUniv @TriIMDPhD @WeillCornell. @WCMAnesthesia resident. I like to run.
New York, NY
Joined August 2012
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Delighted to share my PhD work on the mechanics of protocadherin 15, an inner-ear protein critical for human hearing, out now in @PNASNews!
Read on to hear👂🏼more!
pnas.org/doi/10.1073/pnas.24…
Thank you for the support along the journey @KentsisResearch !
Overall, we showed that the mechanics of PCDH15 are modulated by Ca2+ and that PCDH15 has the appropriate stiffness to be part of the gating spring. The mechanics of the mutant suggest it is unable to convey adequate tension to the channels, likely the mechanism of deafness.
Huge thanks to my co-author @XYDeng97 for making this project a joy to work on! And many thanks to Jim and Joel for their guidance through this journey!
Got the day off clerkships to walk in my PhD graduation ceremony @RockefellerUniv ! Very happy to celebrate this with my friends and family
Congratulations to Rockefeller’s #classof2024, here’s to your next adventure! #PhDone 🔬🍾🧬
Congrats again to @denistorrre and team 🤩
Thrilled to share our work investigating the role of RNA catabolism in regulating ERV expression and stem cell potency! (1/5)
cell.com/molecular-cell/pdf/…
Camila Villasante retweeted
Very proud of this collaboration with my close friend Ivan Marazzi and team. Spearheaded in the lab by a terrific student @denistorrre
We uncover a role for RNA catabolism in regulating euchromatic ERV expression and potency.
cell.com/molecular-cell/full…
Super exciting work out now from @denistorrre et al. on embryonic transcriptomes! 🧬
Excited to share our work investigating the human preimplantation embryo transcriptome by long-read sequencing! Here, we combined @PacBio IsoSeq and @Illumina RNA-Seq, finding thousands of novel isoforms and genes:
nature.com/articles/s41467-0… 1/4
Last month I defended my thesis! I’m very thankful for support of Jim, my lab mates, @RockefellerUniv, and @TriIMDPhD along the way. Officially Dr. Villasante, PhD 👩🏻🎓
And they say a PhD is a marathon—so I ran the @nycmarathon before finishing my PhD to find out if that’s true. Turns out they’re both tough…and I wouldn’t have been able to do either without the support of my amazing family and friends. Thank you!!
I'm very excited to share some of my PhD work, out now as a preprint! Take a look below:
Nanomechanics of wild-type and mutant dimers of the tip-link protein protocadherin 15 biorxiv.org/content/10.1101/…
Camila Villasante retweeted
So excited to finally get to share this with the world! Huge huge credit to my incredible co-author @paigearnold2 and mentor @lydfinley, as well as support from @GSKGradSchool @TriIMDPhD. Many more thanks and metabolism stories to come! 🥲
Our new work describing a “non-canonical” TCA cycle that is engaged in a cell-state dependent manner is out today in @Nature nature.com/articles/s41586-0…. Congratulations to lead authors @paigearnold2 @__btjackson @GSKGradSchool @MSKCancerCenter. A few highlights:
Very happy to announce that I’ve been awarded an F30 fellowship from the @NIDCD to support my work on hearing at @RockefellerUniv and my training as a physician-scientist at @TriIMDPhD !👂🏽 🔬 (1/3)
This fellowship will fund my single-molecule studies in the #HudspethLab at @RockefellerUniv on the mechanics of protocadherin 15, a protein in the inner ear critical to human hearing. (2/3)
Many thanks to the @WeillCornell grants office, the @TriIMDPhD office, and all of the mentors who have helped me along the way—in particular, @oleg8r , @J_Maciejowski , and of course my Twitter-less PI, Jim. (3/3)