@WeaverScience

WEAVER Lab at UT Southwestern Gene-Environment Interactions in Signaling and Regenerative Biology #Proteostasis #Signaling #Aging #Metabolism #Stress #EvoDevo

 UT Southwestern Dallas TX
weaverlabutsw.org/
Joined March 2023
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How do proteins respond when cells are under stress? UT Southwestern scientists uncover new mechanisms that help cells adapt to environmental change. 🔬Read more: bit.ly/3Pswi9w #Research #BiomedicalResearch

Protein coordinates responses to environmental stress

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known...

utsouthwestern.edu
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Excited to share the news!! So proud of my postdoc Wang now promoted to Research Scientist!! Protein coordinates responses to environmental stress: Newsroom - UT Southwestern, Dallas, Texas utsouthwestern.edu/newsroom/…

Protein coordinates responses to environmental stress

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known...

utsouthwestern.edu
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Employing protein tagging, scientists identify interaction networks centered on the #p38 homolog PMK-1 in C. elegans that facilitate phenotypic plasticity during development, in several tissue types, and in response to stresses and aging. @UTSWMedCenter scim.ag/3QUnIAT
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Just published!! Congrat's to my post-doc Wang for getting featured on the cover of Science Signaling. So proud!! So much more to learn about phenotypic plasticity. science.org/eprint/XZZZRR72V…

A Caenorhabditis elegans spatiotemporal proximity atlas reveals the MAPK p38 as a generator of...

Proximity labeling identifies factors that contribute to p38-driven phenotypic plasticity in C. elegans.

science.org
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Our new proteomics method ContinuumID for spatiotemporal proximity atlas and found p38 MAPK is critical for phenotypic plasticity. #Proteomics #Aging #Cancer #Proteostasis #EvolutionaryBiology #Neuroscience
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Don’t miss the new issue of #ScienceSignaling! Scientists uncover the molecular wiring that supports phenotypic plasticity in C. elegans, a new Focus explores community resources that will propel the next era of lipidomics research, and more. scim.ag/4toWMXK
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Check out our highlight of the most recent example of subcellular mitochondrial specialization in @CurrentBiology. Be sure to also check out the beautiful work from David Sherwood's lab cell.com/current-biology/ful…
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Match Day!! So proud of my former MSTP grad student!!! Francisco matched at Yale in Anesthesiology!!! Everyone in the Weaver lab is so proud of you Francisco!!!
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We find UBR-5 E3 ligase connects proteostasis to stemness and motility in aging... link.growkudos.com/1dwpy0mrs…

Proteostasis in stem cell transition to differentiation

We reveal that the balance of poly(A) binding protein PABP-2/PABPN1 and UBR-5 E3 ligase activity levels control the cellular transition out of stemness into differentiation. Elevated levels of PABP-2...

growkudos.com
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These sea turtles dance for joy when they magnetically sense it’s snack time. Learn more on #WorldTurtleDay: scim.ag/4hZLGDf
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Principal Investigator Yuh Min Chook (@yuhminchook) and researchers at @UTSWMedCenter advance our understanding of the diversity of signals that drive nuclear export and how cargo phosphorylation is crucial in regulating nuclear transport and controlling cellular signaling pathways. nature.com/articles/s41467-0…
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Absolutely honored! Just got featured in #career pathways along with Leah at @NatMetabolism Find it here rdcu.be/eiyGG #metabolism #ageing #aging #proteostasis
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I am beyond thrilled to become a Searle Scholar! Thank you @CRI_UTSW, @SJMorrison_ @RalphDeBerardinis (no longer on X), @RobertoZoncu for all your support and mentorship!
Children’s Research Institute at UT Southwestern@CRI_UTSW15 Apr 2025
Congrats, @HijaiShin 👏👏 CRI's newest investigator has been named a 2025 Searle Scholar to support her #relentlessdiscovery & innovative research on lysosomes. From her discovery of LYCHOS to future plans, read more ➡️cri.utsw.edu/shin-named-2025…
Hijai Regina Shin, Ph.D., Assistant Professor in CRI, has been named a 2025 Searle Scholar to support her innovative research on lysosomes.

ALT Hijai Regina Shin, Ph.D., Assistant Professor in CRI, has been named a 2025 Searle Scholar to support her innovative research on lysosomes.

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In this month's Editorial we discuss why basic research is the backbone of advances in medicine and improvements to the human condition - and that basic research needs essential support from government funding. nature.com/articles/s41592-0…

The big picture in science

Nature Methods - Basic science and methods development is essential to ensure that lifesaving advances and improvements to the human condition continue moving forward. Such research needs strong...

nature.com
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G&D’s Editor-In-Chief, Professor Andy Dillin is attending the 2025 @ASBMB Annual Meeting in Chicago. #ASBMB25 #MakeItPossible If you’d like to share your work with us or learn about the journal, feel free to drop by or reach out at [email protected] @GenesDev @dillinlab
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It was a lot of fun today getting to talk with the students about life and career challenges! Thanks Arnaldo and Leah for hosting this! xitter.cf/ADiaz_PhD/status/19002…
Dr. Arnaldo Díaz@ADiaz_PhD13 Mar 2025
We cordially invite our community to our upcoming STORIES event on April 8. Join us as we welcome Dr. Benjamin Weaver, who will share his inspiring journey in science. Check out the flyer for details.
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With its UFO-like display, the cuttlefish may look like it’s trying to get attention—but its intent is anything but. The undulating black stripes confuse prey, making the creatures all but invisible to crabs and other victims: scim.ag/4c91RMB @NewsfromScience
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I am so excited to share that our paper on ERK activation dynamics in the maturing oocyte has just been published on @CellReports today! Shoutout to all the authors (@sarur2 , @DDas85 , Shin-Yu Chen, and Hongyuan Li)! @UTGSBSGnE @MDA_UTHGrad cell.com/cell-reports/fullte…

ERK activation dynamics in maturing oocyte controls embryonic nuclear divisions in Caenorhabditis...

RAS/ERK signaling is necessary for oocyte development but is turned off during the oocyte-to-embryo transition across species. Baek et al. show that aberrant reactivation of ERK in C. elegans leads...

cell.com
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Ben Weaver retweeted
PNASNews@PNASNews7 Nov 2024
A species of comb jelly (Mnemiopsis leidyi) can age backward when stressed, reversing its development from a sexually mature life cycle stage to an earlier larval stage—a finding relevant to the study of aging and rejuvenation in animals. In PNAS: ow.ly/qRqQ50U1AtH
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MEF2 is upregulated during cardiac hypertrophy and is required for normal post-natal growth of the myocardium: Current Biology cell.com/current-biology/ful… 25 years ago this week, the Megeney lab published its very first paper and the story has stood the test of time!

MEF2 is upregulated during cardiac hypertrophy and is required for normal post-natal growth of the...

In mammals, growth of the fetal heart is regulated by proliferation of cardiac muscle cells. At later stages of pre-natal life, this proliferation diminishes profoundly [1,2] and the dramatic...

cell.com
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