@opentargets maintainer. Lead frontend developer @emblebi 🇨🇷
Cambridge, England
Joined June 2013
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The 3D viewer, variant overlay, amino acid colour schemes — none of it was built for a chat context.
Getting it into a sandboxed iframe, sharing React context across component boundaries, reporting its own height dynamically... that took real untangling.
Once the infrastructure is in place, each new widget is essentially free.
The visualisation already exists in the platform. You're just giving it a new address.
Built with Claude Code + the MCP-UI framework + existing Open Targets components.
Post 2 of a series(?). Pura vida 🔭
#AlphaFold #AI #MCP #ReactJS #DataViz
The 3D protein structure viewer 🚀
@GoogleDeepMind #AlphaFold predicted the structure. @OpenTargets Platform stores where the variant sits. This prototype connects both — rendered directly in the conversation.
No screenshot. No link. The structure lives in the chat.
Finally I can properly explore the mcp-ui pattern. Pretty interesting how the development of new components (complex ones) will change dramatically the way data is loaded into them. Exiting times🔥 building a demo using @opentargets.orgcomponents.
Ref: mcpui.dev
Doing a recap of the week. It was amazing to attend my first Remix London meetup. Thanks to
@CloudflareDev for organising!
Great to check out such nice tooling as MCPS and Cloudflare workers. A lot of ideas for building new tools for @OpenTargets 🔥
Related. This is a proof of concept for an MCP server for the Open Targets API. Just checking-in github.com/carcruz/ot-mcp-pr…
Excited to share our "Associations on the Fly" paper in Oxford Bioinformatics!🧬
In @OpenTargets we built this tool to visualise multi-level data on a single screen, helping researchers navigate complex evidence without switching context.
Check it out: academic.oup.com/bioinformat…
There are many improvements and new features in the latest @OpenTargets release. Genetics here we go 🚀
New data visualizations, accessible color pallets, and full UI refresh. Not to say, the addition of @observablehq Plot.js s, the upgrade to @vite_js v6. React Router v7 🔜
Release Notes blog.opentargets.org/open-ta…
Carlos Cruz retweeted
With the gget opentargets module, you can now interact directly with the Open Targets database from a Python or command line environment
Developed by @NeuroLuebbert, gget is a free, open-source tool enabling efficient querying of large genomic databases
blog.opentargets.org/case-st…
ALT On a photo of concentric blue circles opening out onto an orange and grey building, text reads: Case study, easily query Open Targets data with gget
Carlos Cruz retweeted
Happy birthday to our colleagues in @OpenTargets 🥳
Enjoy a well deserved celebration after 10 years of pushing the boundaries of drug discovery.
Here’s to the next 10 years!
Happy 10th birthday Open Targets! 🎉
Thank you to everyone who has worked to make Open Targets what it is today.
Here's to the next 10! 🥂
#OpenTargetsAt10
Para que los costarricenses lo leamos todos los días. Hagámonos cargo.
Thanks to the @OpenTargets tech team for supporting the organic development of features and constant refactoring in AotF
Seeing the tool's progress over every release demonstrates our dedication and commitment to our users and our confidence in our team's creativity
🤘🚀
🚨 Open Targets Platform 24.09 is out today!
ALT Graphic for 24.09 composed of multiple boxes featuring: associations filtering with logos from ChEMBL, Uniprot, Ensembl, Human Protein Atlas, Gene Ontology, and Reactome, 941 targets with known safety events, FinnGen R11 evidence for 336 associations added to gene burden, 36,740 gene burden evidence in total, OpenAI gpt 4o mini, Azure open datasets, and UI updates for DepMap
Carlos Cruz retweeted
One of my favorite PhD theses (about architectural complexity) literally cites
"Some engineers in the study had 10x more output, this drowned out all other measurable effects"
as a big challenge in its methodology section
“"10X engineers are a myth, and believing in them is harmful." Quite the contrary. In many teams, a small fraction of the workforce often generates the majority of outcomes. Recognizing and nurturing high-performing individuals isn't just realistic—it's crucial.”
My brother from another mother is right
Happy to be part of the history of @OpenTargets 👏🎉
Double digits!
Open Targets was founded 10 years ago today 🎂
Over the next year, we'll be reflecting on key achievements and looking forward to the next decade and beyond... #OpenTargetsAt10
Congratulations to the whole team at Open Targets, past and present!🥂
ALT Graphic featuring the number 10 and an explosion of blue-coloured science elements such as DNA, cells, molecules. Text reads: Celebrating 10 years of Open Targets
Carlos Cruz retweeted
Happy #InternationalMotherLanguageDay!
Our team celebrated by sharing some of their favourite words and phrases with each other — how many do you know?
🇺🇸🇮🇹🇨🇳🇪🇸🇮🇷🇩🇪🇰🇪🇬🇧🇷🇺🇮🇳🇨🇴🇵🇱🌍