My lab studies the interplay between cancer metabolism and cell cycle dysregulation. Professor. The Wistar Institute
Philadelphia, PA
Joined May 2017
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Our lab is expanding and hiring both a postdoc and staff scientist! We study how metabolism and cell cycle states drive tumor progression, therapy response, and immune interactions. Philly is a great place to live and do research! See more at: airdlab.com.
Katherine Aird retweeted
Ever wonder if tRNAs can regulate the identity of a cancer cell?
@HsiehLab @FredHutch postdoc @yeonsookim_phd did and discovered a single tRNA that can control lineage dependency and drug sensitivity in prostate cancer published today @Nature: nature.com/articles/s41586-0…
Katherine Aird retweeted
Our latest paper has just been published in @Aging_Cell 🥳
onlinelibrary.wiley.com/doi/…
Extracellular vesicles (EVs) from senescent cancer cells are not just passengers of the SASP. They are both necessary and sufficient to spread senescence to neighboring cells 🧵
Katherine Aird retweeted
Our latest preprint, from @eerinberr is live:
Cytoskeletal disassembly by optogenetic control of RhoA signaling termination.
biorxiv.org/content/10.64898…
Katherine Aird retweeted
I am extremely proud to share this paper from @_Christina_Sch "Integrated metabolomics data analysis to generate mechanistic hypotheses with MetaProViz" in @JulioSaezRod ! Congratulations to all involved!
link.springer.com/article/10…
Katherine Aird retweeted
From @airdlab and team: “The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming” nature.com/articles/s43587-0…
Katherine Aird retweeted
Excited to share our work, now in @Nature! Delighted to have co-led this study with co-first author @AntonioAhnNZ under the supervision of @shomgoel at @PeterMacCC @PeterMacRes and the University of Melbourne @uommedia
Open access:
nature.com/articles/s41586-0…
Katherine Aird retweeted
Immune surveillance and immune evasion of senescent cells dlvr.it/TTyX7y
Katherine Aird retweeted
Our new paper is out in @CellReports 🎉
Congrats to @MahlkeMegan, and the whole team and collaborators! Check it out here:
cell.com/cell-reports/fullte…
Katherine Aird retweeted
The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming
Thank you to the @airdlab & team for choosing Twist DNA to support this research!
nature.com/articles/s43587-0…
Katherine Aird retweeted
Acquisition of Centromeric Features Supports Telomere Integrity doi.org/10.1158/2159-8290.CD…
A #ResearchWatch summary of a recent study by Ragini Bhargava, Yael Nechemia-Arbely, Roderick J. O’Sullivan, and colleagues.
Thrilled to see our work on senescence & metastasis out! We found that chemotherapy increases ovarian cancer metastasis in a paracrine manner via fructose. Dietary fructose is sufficient to increase metastatis. This work has multiple implications related to both chemo and diet.
Online now!✨Cole et al identify fructose as a component of the therapy-induced SASP in senescent ovarian cancer cells and show that it reprograms cancer cells in paracrine, promoting detachment and metastasis @airdlab nature.com/articles/s43587-0…
Also big thank you and congrats to all coauthors and collaborators. @BioYupi @ApoorvaUboveja @mzspectrum @NadineHempel @CoffmanLab @oesterreichs @healthspan_AUG @zervanto and many others!
Extra special thanks to @bitlerlabucd who was always there to give feedback, selflessly provide data, and cheer this work on. We are on a crusade to change the way we think about chemo use in ovarian cancer
We are grateful that this work was supported by @theNCI, CDMRP, @UPMCHillmanCC, @PittTweet, @TheWistar
Katherine Aird retweeted
Good Sunday, all. Here is a superexciting summary of papers in #cancermetabolism and #mitochondrialbiology: biomed.news/bims-camemi/2026… @Bims_BiomedNews @mitoworld_org #keepreading
"When you argue with reality, you lose, but only 100% of the time."
-Byron Katie
Another article with real world stats about gender bias in publication. Women corresponding authors are more likely to be desk rejected. The cumulative effects of rejection at all stages for women corresponding authors is striking.
Editorial and peer review dynamics at elite general science journals | Science Advances science.org/doi/10.1126/scia…
Katherine Aird retweeted
Editorial and peer review dynamics at elite general science journals | Science Advances science.org/doi/10.1126/scia…
.@ApoorvaUboveja is on a role! In addition her beautiful 1st author Nature paper, she just received an exceptional score on her K99!! I couldn’t be more proud of this amazing scientist and feel honored to be a part of her journey. Congratulations Apoorva!