Uro-Onc @VCUUrology @VCUMassey via @NCICCR_UroOnc, @utswurology residency, @nyugrossman MD. On twitter for urology, misc. sports/news/zillow content.
Joined May 2020
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- Following296
- Followers325
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Alexander Kenigsberg retweeted
The ? begs for a cleaner RCT. LUCKILY @theusinghal and @swog have created S2613 which has the “do or don’t do question” built into cohort A and further explores the role in (mi)N+ disease on PSMA PET. Hopefully urologists are on board w/this trial and we start answering some ?s
Alexander Kenigsberg retweeted
Massey becomes one of two sites in VA to offer single-port robotic surgery for prostate cancer.
masseycancercenter.org/news/…
Please publish the series. Would be genuinely novel, supposedly with an enormous n. Would be nice to know which patients were treated, by what modality. Perhaps there is learning here, perhaps exaggeration. I believe the focal community would welcome the insight.
If I had a nickel for every time a friend asked me about prostate focal therapy, I’d be rich.
I’ve personally managed 20–30 intraprostatic failures after focal therapy. One patient ended up with a permanent Foley after salvage RT. Nearly all required medical castration, which many likely could have avoided with definitive therapy upfront. The downstream consequences are real.
Our group ultimately decided not to offer focal therapy outside of very niche scenarios (for example select reirradiation not ideal for partial or full gland SBRT). If I were a patient, I might assume focal therapy is better than standard options too. The marketing is that good. #OncTwitter
Exciting times for @VCUUrology1 !
Alexander Kenigsberg retweeted
🚨 NEW IN @EUplatinum! 🚨
The largest analysis of focal therapy by Imperial Prostate and UK colleagues, reporting 1⃣0⃣-year outcomes after focal HIFU and cryotherapy in 3⃣4⃣7⃣7⃣ men 🔥🧊
Led by @AJWLight @LondonProstate1 @TaimurShah
Read for free: europeanurology.com/article/…
So much fun hosting @vourganti @VCUUrology! Powerhouse talks and amazing clinic teaching. Thrilled that such a great guy is pushing our field forward. Can’t wait to see what awesome innovations he comes up with next and for future collaboration! @FocalSociety
So grateful to join the dynamic and talented group at @VCUUrology today as Visiting Professor to their Dept. Many thanks go to my good friend @apkenigsberg and Chair Adam @klaussner for the generous opportunity to share ideas towards the future of prostate cancer precision care.
Alexander Kenigsberg retweeted
Great SUO meeting and nice to catch up with the NCI “FFF”’s and trainees doing great things in uro onc across the country @LoyolaUrology @theNCI @UroOnc
Two-handed endoscopic surgery is a game changer! No doubt the applications will extend beyond en bloc resections. Can’t wait until this is readily available and can hopefully bring to @VCUUrology
Hot off the press!! First reported case series of transurethral robotic en bloc resection of bladder tumour using the Virtuoso Endoscopy System (VES). Published in @EurUrolOncol today! (1/n) #ERBT #UroSoMe
Alexander Kenigsberg retweeted
Agree Andrew.
What people are failing to consider when looking at the data:
1) PSA is cheap, non-invasive and very sensitive
2) The decision to biopsy is different now than it was 23 years ago. We use PSA density, MRI, genetic tools
3) Utilization of Active surveillance is MUCH higher now. Cancer don’t equate to treatment
4) We start screening earlier and stop screening earlier now
5) we have better RT planning, higher utilization of robotics, developing focal therapies
6) people fail to realize that it wasn’t until about 15 years ago the we really started to develop an effective way to treat metastatic prostate cancer.
This same study conducted now would provide less harm and atleast similar benefit. But is it truely reasonable to conduct massive RCTs when the answer is right in front of us?
I would argue no. It is cost prohibitive.
PSA must have a role. It certainly needs to be better and more risk adjusted.
But those calling to stop all PSA are missing the point.
Alexander Kenigsberg retweeted
Exciting 23 year update from the ERSPC #prostatecancer screening trial from @MoniqueRoobol and team, and a great editorial @VickersBiostats. NND is down to 12 and still falling! And the benefit:harm ratio would be even better w/ modern screening/dx/tx pathways.
At 23 years of follow-up, population-based PSA screening of asymptomatic men led to a sustained reduction in prostate cancer mortality, although overdiagnosis remains a concern. Full ERSPC study results: nej.md/42YYsg7
Editorial: Early Detection of Prostate Cancer — Time to Fish or Cut Bait nej.md/47tKwfA
ALT Original Article | Oct 30, 2025 European Study of Prostate Cancer Screening — 23-Year Follow-up Figure 2B. Prostate Cancer–Specific Mortality. The NEJM identity sits at the bottom.
Alexander Kenigsberg retweeted
Younger patients looking for focal therapy
✅ most to gain regarding preservation of function
❎ most to lose from potential oncological outcomes
Careful counselling from the beginning is key #FOCAL2025
Alexander Kenigsberg retweeted
#FOCAL2025 is in 1 WEEK! Join us live or virtually from October 9-11 for 3 days of outstanding CME content with the world's leading experts in #FocalTherapy
Secure Your Spot Now: focaltherapy.com
@arvinkgeorge @AbhinavSidana
Alexander Kenigsberg retweeted
Massey is now offering a new, innovative procedure for prostate cancer biopsies, performing transperineal biopsies in downtown Richmond. This option is considered significantly safer than transrectal biopsies.
masseycancercenter.org/news/…
Alexander Kenigsberg retweeted
Case Study by W.S. Azar et al.: LLM-Mediated Data Extraction from Patient Records after Radical Prostatectomy nejm.ai/4dw8Boz
#HealthIT #MedicalAI
ALT Table 1. Performance Metrics of LLM in Extracting Pathological Data across Variable Types.
ALT Figure 3. Descriptive Statistics of Study Variables.
Fantastic resident and even better guy! Will be missed @VCUUrology when he leaves (but looking forward to training him up this chief year). @SUO_YUO
Alexander Kenigsberg retweeted
Alexander Kenigsberg, MD, (@apkenigsberg) discusses a new option for treating prostate cancer: robotic high-intensity focused ultrasound. #pcsm | @VCUUrology @VCUMassey
hubs.li/Q03pK5bD0
Alexander Kenigsberg retweeted
Excited to share our latest study in @NEJM_AI ! 🚀
We introduce NTEP, a @NIH platform that uses large language models to extract data from unstructured medical reports with 99.8% accuracy – bridging AI with real-world medical research
🔗 Free access: ai.nejm.org/stoken/default+d…
Alexander Kenigsberg retweeted
President Biden’s diagnosis of metastatic #prostatecancer is serious—but in the past 20 years, 5-year survival has improved markedly thanks to better imaging, advanced therapies, and more effective care. Often men live many years—and sometimes decades—with a terrific quality of life.
Former President Biden has been diagnosed with an aggressive form of prostate cancer just months after his first term came to an end.
Read more: on.wsj.com/3EYSJyd
Focal Fridays @VCUUrology @VCUMassey . Very satisfying to see post-HIFU treatment effect on contrast-enhanced ultrasound. @FocalOneHIFU @FocalSociety