David B. Solit, MD (@DSolit) header
David B. Solit, MD (@DSolit) profile picture

David B. Solit, MD

@DSolit

Chief, Molecular Medicine Service; Geoffrey Beene Chair; Co-Director, Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center

 New York, USA
mskcc.org/research-areas/labs/david-solit
Joined April 2010
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Photo by David B. Solit, MD (@DSolit)Photo by David B. Solit, MD (@DSolit)Photo by David B. Solit, MD (@DSolit)Photo by David B. Solit, MD (@DSolit)Photo by David B. Solit, MD (@DSolit)Photo by David B. Solit, MD (@DSolit)Photo by David B. Solit, MD (@DSolit)Photo by David B. Solit, MD (@DSolit)Photo by David B. Solit, MD (@DSolit)Photo by David B. Solit, MD (@DSolit)
It has been a year since my last update on the prospective MSK-IMPACT/ACCESS sequencing cohort, now >120,000 tumor/cfDNA samples analyzed. Thanks to the patients, docs, nurses, techs, data scientists who have contributed. So where are we going next:
Image from David B. Solit, MD (@DSolit)
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Dan Landau (@landau_lab) profile picture
Dan Landau@landau_labOct 29
Faculty ad is out, please help spread the word Come #DreamBig together, without a doubt, in the best city in the world! jobs.sciencecareers.org/job/…
Tenure-Track Assistant/Associate Professor - New York

Tenure-Track Assistant/Associate Professor - New York

Weill Cornell Medicine - Tenure-Track Assistant/Associate Professor Department of Systems and Computational Biomedicine | New York, NY Weill Cornel

jobs.sciencecareers.org
Dan Landau (@landau_lab) profile pictureDan Landau@landau_labSep 1
Replying to @landau_lab
🚨We're recruiting! Calling all bold & original thinkers! Folks with imagination, drive & the (rare) ability to find the thin seam where the fantastical and real meet. Come join a thriving science community, in, beyond a shadow of a doubt, the greatest city in the 🌎 @nyknicks
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David H Aggen, MD PhD (@Dr_Aggen) profile picture
David H Aggen, MD PhD
@Dr_AggenOct 23
As discussed at #ESMO26, data on EV+P in bladder cancer with variant histology remain limited. Together with Emory and Dr. Jacqueline Brown, we’re studying EV+P in tumors with aberrant histologic features including with squamous, plasmacytoid, and glandular features. MSK PI: Dr. Sam Funt. @OncoAlert More info here: mskcc.org/cancer-care/clinic… clinicaltrials.gov/study/NCT… #bladdercancer #esmo2026
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Jonathan Rosenberg MD (@DrRosenbergMSK) profile picture
Jonathan Rosenberg MD@DrRosenbergMSKOct 20
The MSKCC Genitourinary Oncology Service is looking for a motivated, patient-centered, clinical investigator with a focus on urothelial cancer. Join a great team focused on eradicating GU cancers! msk.wd108.myworkdayjobs.com/…
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Himanshu Nagar (@HimanshuNagarMD) profile picture
Himanshu Nagar
@HimanshuNagarMDJul 9
Join MSK faculty Oct. 8–9, 2026 for a hybrid 2-day course on the latest advances in multidisciplinary prostate cancer care—from risk assessment and imaging to local and systemic therapies. Attend onsite in NYC or virtually via Zoom. #ProstateCancer Register here: mskcc.cloud-cme.com/course/c…
Image from Himanshu Nagar (@HimanshuNagarMD)
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Himanshu Nagar (@HimanshuNagarMD) profile picture
Himanshu Nagar
@HimanshuNagarMDSep 11
🚨 We’re hiring at MSK! 🎯 Director, Metastatic Disease Team 👥 Lead ~20 faculty 🧪 Drive innovative trials 🔬 ~50% research time (track-dependent) 🌐 Shape care across @MSKCancerCenter Help define what’s next in @MSK_RadOnc. 🚀 Contact @seanmmcbride if interested. Click here for more details: msk.wd108.myworkdayjobs.com/…
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James J. Harding, MD (@HardingJJMD) profile picture
James J. Harding, MD@HardingJJMDJul 4
Congratulations @CowzerDarren. Great deep dive #biliarytractcancer #genomics outcomes and resistance! @MSK_DeptOfMed @MSKCancerCenter @MskccCMO @DSolit @GABOUALFA @EileenMOReilly
Clinical Cancer Research (@CCR_AACR) profile pictureClinical Cancer Research@CCR_AACRJun 27
Now online: Molecular and Clinical Determinants of Targeted Therapy Treatment in Biliary Tract Cancer doi.org/10.1158/1078-0432.CC…
Image from Clinical Cancer Research (@CCR_AACR)
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ari hakimi (@arihakimi) profile picture
ari hakimi@arihakimiJun 4
Why do VEGFR-TKI + IO combinations produce impressive responses in ccRCC but often fail to achieve the long-term durability seen with dual checkpoint blockade? Check out our lab's latest in @Cancer_Cell led by the incredible Lyn Vuong! cell.com/cancer-cell/fulltex…
Hypoxia shapes both therapeutic response and resistance in metastatic clear cell renal cell...

Hypoxia shapes both therapeutic response and resistance in metastatic clear cell renal cell...

Vuong et al. comprehensively profile the tumor microenvironment in mouse and human ccRCC after VEGFR-TKI and ICI therapy to reveal that SPP1+ TAM recruitment reflects true tissue hypoxia and acts as...

cell.com
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Congratulations to Dr. Martin Weiser, who has been selected to serve serve as the next Chair of the Department of Surgery at MSK. Dr. Weiser currently holds the Stuart H.Q. Quan Chair in Colorectal Surgery, is a world-renowned academic colorectal surgeon, and has held a number of important leadership roles in his 25 years on the faculty at MSK, including serving for the past 10 months as the Acting Department Chair. Join us in welcoming Dr. Weiser to the role of Chair of the Department of Surgery by commenting below. 👏
Image from Memorial Sloan Kettering Cancer Center (@MSKCancerCenter)
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Ziad Bakouny, MD, MSc (@ZiadBakouny) profile picture
Ziad Bakouny, MD, MSc@ZiadBakounyMay 31
Really awesome poster by urologic oncology fellow extraordinaire @VinceDAndreaMD with @DrDarrenFeldman @DSolit #SamFunt on genomic determinants of cisplatin resistance in germ cell tumors! @MSKCancerCenter @UrologyMSK @MSK_DeptOfMed @ConquerCancerFd @ASCO #ASCO26
Image from Ziad Bakouny, MD, MSc (@ZiadBakouny)
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Jiaqian(Josie) Luo (@luo_jiaqian) profile picture
Jiaqian(Josie) Luo@luo_jiaqianApr 24
A truly memorable #AACR26! Honored to present our work on bladder cancer lineage plasticity and grateful to receive the Scholar-in-Training Award. Huge thanks to my mentor @DSolit, collaborators, and labmates for their guidance and support #BladderCancer #CancerResearch
Image from Jiaqian(Josie) Luo (@luo_jiaqian)
Image from Jiaqian(Josie) Luo (@luo_jiaqian)
Image from Jiaqian(Josie) Luo (@luo_jiaqian)
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Today, MSK physician-scientist Dr. Sarat Chandarlapaty shared his research on how #cancer develops resistance to #HER2 antibody-drug conjugates during a session at #AACR26.
Image from Memorial Sloan Kettering Cancer Center (@MSKCancerCenter)
Image from Memorial Sloan Kettering Cancer Center (@MSKCancerCenter)
Image from Memorial Sloan Kettering Cancer Center (@MSKCancerCenter)
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On the #AACR26 stage this morning: Dr. Yelena Janjigian, Chief of MSK's Gastrointestinal Oncology Service, will share her expertise on the latest advances in #cancer #immunotherapy. @MSKCancerCenter @AACR @YJanjigianMD ⏰ 10:15 a.m. PDT bit.ly/4exbXKp
Image from MSK Department of Medicine (@MSK_DeptOfMed)
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Carissa Chu (@CChuMD) profile picture
Carissa Chu@CChuMDApr 21
Great to see @DSolit today at #AACR26. Truly incredible mentor along with @jonchou05 So much on plasticity in bladder cancer yet to explore. Cut to Tamilla and I continuing to look through our data over tapas 🤓 💃🏻
Image from Carissa Chu (@CChuMD)
Image from Carissa Chu (@CChuMD)
Image from Carissa Chu (@CChuMD)
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Happening soon at #AACR26: Dr. David Solit is leading a session sharing how the @AACR international registry Project GENIE® is advancing #cancer research. @MSKCancerCenter @DSolit ⏰ 2:30 p.m. PDT bit.ly/4sIBMuB
Image from MSK Department of Medicine (@MSK_DeptOfMed)
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Every medical breakthrough begins with a decades-long journey in the laboratory, a key message shared during #AACR26. Our MSK #SavedbyScience series, captures the emotional meetings between patients and the scientists, including physician-scientist and AACR presenter Dr. @DSolit, whose years of research have given them new hope. Watch more Saved by Science stories on YouTube: bit.ly/4bRHtSe @AACR
Image from Memorial Sloan Kettering Cancer Center (@MSKCancerCenter)
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MSK physician-scientist Dr @DSolit presented about advancing target discovery for rare cancers through institutional-scale molecular profiling and social media outreach at #AACR26. @AACR
Image from Memorial Sloan Kettering Cancer Center (@MSKCancerCenter)
Image from Memorial Sloan Kettering Cancer Center (@MSKCancerCenter)
Image from Memorial Sloan Kettering Cancer Center (@MSKCancerCenter)
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Wungki Park, MD MS (@CentralParkWMD) profile picture
Wungki Park, MD MS
@CentralParkWMDMar 25
1/n Setidegrasib the first-in-human, first-in-class, KRAS G12D-targeted protein degrader #TPD Our KRAS G12D degrader study is now published in the New England Journal of Medicine @NEJM nejm.org/doi/full/10.1056/NE… A new way to target KRAS G12D - one of the most common oncogenic drivers across cancers. – at Guadalupe, AZ
Image from Wungki Park, MD MS (@CentralParkWMD)
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James J. Harding, MD (@HardingJJMD) profile picture
James J. Harding, MD@HardingJJMDMar 20
Thank you @GABOUALFA, @MSK_DeptOfMed for many years of mentorship/support in #HPB cancers. Amazing to win this @theNCI #R01 award. @EileenMOReilly , @YJanjigianMD @DSolit @OlcaBasturk @MskccCMO @MSKBiostats @MSKCancerCenter
Ghassan Abou-Alfa (@GABOUALFA) profile pictureGhassan Abou-Alfa@GABOUALFAMar 20
Congratulations @HardingJJMD on your #R01. @MSKCancerCenter @MSK_DeptOfMed and all colleagues are happy for you!
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Ghassan Abou-Alfa (@GABOUALFA) profile picture
Ghassan Abou-Alfa@GABOUALFAMar 20
Congratulations @HardingJJMD on your #R01. @MSKCancerCenter @MSK_DeptOfMed and all colleagues are happy for you!
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David H Aggen, MD PhD (@Dr_Aggen) profile picture
David H Aggen, MD PhD
@Dr_AggenMar 14
Enjoying a Saturday at #NYGU #GOTOPER with @DSolit reviewing ADC target expression in variant histology bladder cancer. Fantastic work in collaboration with @h_alahmadie #GU #NYGU26
Image from David H Aggen, MD PhD (@Dr_Aggen)
Image from David H Aggen, MD PhD (@Dr_Aggen)
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