Business consultant and popular culture and music researcher. Artificial intelligence researcher
Santa Barbara, CA
Joined February 2013
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Eldon Edwards retweeted
A 37-year-old woman with 10 years of abdominal pain.
—The AI makes the diagnosis and recommends a successful treatment.
—The physician "diagnosed a patient with a condition I had never diagnosed before and started treatment largely on the basis of the output of a chatbot."
In today's @NEJM
nejm.org/doi/full/10.1056/NE…
Eldon Edwards retweeted
There still in no approved or highly effective treatment for postural orthostatic tachycardia syndrome (POTS), which can be debilitating.
Now there's hope with very encouraging results of a Phase 2 randomized trial: an antibody vs natriuretic peptide receptor 1 (NRP-1)
firstwordpharma.com/story/84…
Eldon Edwards retweeted
But we also don't want to stop agents from doing relevant academic research (or even commercial research, since it might mention your product) with too many gates and barriers.
In any case, I donated to the Internet Archive for my use of the commons, but better solutions needed.
Eldon Edwards retweeted
The traffic from agent swarms doing research is going to be quite large, they are relentless. I had Fable 5.2 reconstruct WH Auden's 1941 poetry class. It found an obscure, relevant book on the Internet Archive, which it read a line at a time by doing repeated full text searches.
Eldon Edwards retweeted
AI slop replies, ranked by annoyingness:
6) Repeating the post
5) LLM knows more than the account should about a topic
4) Lame semi-joke
3) "X is the part I would keep/everyone misses..."
2) "As a marketer/builder/dentist, I see this in my own..."
1) Questions faking "curiosity"
Eldon Edwards retweeted
November 11, 1926: U.S. Highway 66, also known as Route 66, was officially commissioned.
The 2,448-mile highway ran from Chicago through Missouri, Kansas, Oklahoma, Texas, New Mexico and Arizona, before ending in Santa Monica, California.
Eldon Edwards retweeted
November 13, 1966: Comedian Flip Wilson makes his debut appearance on "The Ed Sullivan Show"; he returns 10 times.
Eldon Edwards retweeted
"You see the model called hydrogen is equivalent to the models called sonnet and luna and spark, but the model called fable is like wonder and astra and carbon (but it was like argon)"
"Wait, why do you look confused?"
Eldon Edwards retweeted
Complex systems fail suddenly and catastrophically for complex reasons.
This is a paper I post every six months as it is worth rereading; the 18 reasons complex systems fail.
Complex systems fail for complex reasons, and only adaption & learning by organizations, as well as individual "actions on the sharp end" keep us safe. researchgate.net/publication…
Eldon Edwards retweeted
As our brain ages, there is disruption of the flow of cerebrospinal fluid during sleep @NatureAging
nature.com/articles/s43587-0…
Eldon Edwards retweeted
Got to see student presentations today at the Generative AI Studio at Penn. It was a visceral way to feel how far creative people can now get using AI. Already, almost every project from an individual was 10x further along than a fully done team project from three years ago.
Eldon Edwards retweeted
TOM MIX (1880-1940) appeared in 291 films, all but nine of which were silent movies.
He was one of Hollywood's first Western stars and helped define the genre as it emerged in the early days of the cinema.
Eldon Edwards retweeted
ClinicalAge, an AI-derived metric from longitudinal electronic health records, varies widely from an individual's chronological age. And it's correlated with risk of many diseases and cancers, as shown below, from 2 huge cohorts @uk_biobank @LancetDigitalH
thelancet.com/journals/landi…
Eldon Edwards retweeted
This is applicable on a daily basis.
The irony of AI's remarkable predictive power and its unpredictability
New cover @TheEconomist
Eldon Edwards retweeted
How multimodal AI, combined with blood test omics via "liquid biopsies," will transform cancer monitoring and enable earliest detection.
open-access @CellCellPress
cell.com/cell/fulltext/S0092…
Eldon Edwards retweeted
Mapping a path to prevent breast cancer
@ScienceMagazine
Ductal carcinoma in situ (DCIS) is common and can be a precursor to invasive cancer. Elegant single cell and spatial omics work here tells us how DCIS progresses, earlier than previously anticipated, and lays a foundation for prevention
science.org/doi/10.1126/scie…
Eldon Edwards retweeted
Neat expansion on Portals to visualize The Culture (I had one Banks world in the original 466 Portals, but no GSVs etc.)
Original version: portals-endless-worlds.netli…
Repo: github.com/emollick/ai-porta…
Inspired by @emollick’s Portals, I used his repo and Fable to build Portals for Iain M. Banks Culture novels: sonic-sphinx-9qsd.here.now #theculture #iainmbanks
Eldon Edwards retweeted
Leaving aside everything else about this research done by METR at Anthropic, it validates vibe-testing.
It is my experience with the quality of the past years of Anthropic AI models (& AI consensus on X). Yes, NewSonnet 3.7 was the most obviously above expectation model of 2025.
Eldon Edwards retweeted
We worked with teachers to help build this initial version. It is neutral as to the models or technologies, so adapt it as needed.
And the last appendix is a prompt that hands the paper to an AI agent and tells it to go build its own version of Primer. It is a paper you can run.
Eldon Edwards retweeted
🚨 Our Generative AI Lab is releasing Primer: an agent-driven system where a teacher talks through lessons & gets back a playable simulation for their students, grounded in pedagogy. We hope educators & researchers build on it. Paper/prompts/code are open: gail.wharton.upenn.edu/prime…
