Building the world’s first AI-Driven Digital Organism (AIDO). We're hiring: https://xitter.cf/t.co/JwdGBJvhkL

Palo Alto | Paris | Abu Dhabi
Joined September 2024
Today we're releasing a preview of AIDO Cell, a world model of the human cell. It simulates one cell across DNA, RNA, protein, through regulatory networks and whole-cell behavior. Not four models handing results to each other. One system.
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The ADIA Lab Symposium opens in Abu Dhabi on Monday, October 26. @dasongle will be delivering a keynote on day two. @adia_lab is an independent research institute working in data and computational sciences, and this is its flagship event. Le's talk is AIDO Cell: A General-Purpose Simulator for Cell Biology.
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GenBio AI retweeted
Drugs that fail in clinical trials most often fail on efficacy or unexpected toxicity. In @Forbes, our CTO @dasongle traces both to one gap: no tool can yet predict how a molecule behaves inside a living cell. That gap is what AIDO Cell is for. bit.ly/3VjUoGn
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Drugs that fail in clinical trials most often fail on efficacy or unexpected toxicity. In @Forbes, our CTO @dasongle traces both to one gap: no tool can yet predict how a molecule behaves inside a living cell. That gap is what AIDO Cell is for. bit.ly/3VjUoGn
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Replying to @dasongle
@dasongle is a featured panelist on the opening panel at Molecules, Models & Agents in San Francisco on Monday, October 5. From Data to Discovery: AI Across Digital Health and Digital Biology, moderated by @dr_alphalyrae of @NVIDIA NVentures, with Michael Aratow of @EllipsisHealth and @kavi_deniz of @tamarindbio. #SFTechWeek
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GenBio AI retweeted
Eric Xing
@ericxingSep 17
We discussed fundamental issues in the definition, model architecture, computational algorithm, and meaningful evaluation/qualification of a fully steerable virtual cell that is multi-modal, multi-scale, dynamic, and stateful. @dasongle , @genbioai , @mbzuai , @CarnegieMellon cell.com/cell/fulltext/S0092…
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Out today in @cellpressnews: "A world model of the virtual cell," from our co-founders @ericxing and @dasongle. Their definition of a virtual cell is a stateful, multi-modal, multi-scale simulator, judged on whether it stays coherent across a sequence of interventions. Open access: cell.com/cell/fulltext/S0092…
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A model that makes one prediction and resets only captures a snapshot. AIDO Cell holds the cell's state: perturb it, read it out, then further experiment on the cell you just changed. @DrugDiscovNews on where the virtual cell came from, what's left to prove and how world models are redefining cellular simulation: drugdiscoverynews.com/what-i…
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More coverage from @fwpharma, @TLDRnewsletter, @BigDATAwireNews, The Innermost Loop (by @alexwg), and other prominent newsletters across AI and biotech.
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@LongevityTech asks: “Can AI put the cell back together?” They look at how AIDO Cell links DNA, RNA, protein and whole-cell behavior, and how it ‘remembers’ what has already happened to the cell previously: longevity.technology/news/ca…
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@statnews: AIDO Cell is built to predict how a cell’s overall machinery responds to a drug or a gene knockout. The publication compares it to AlphaFold but for a different domain and with added complexity: statnews.com/2026/08/18/davi…
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It’s been a week since we revealed AIDO Cell. Here’s some of the coverage that encapsulates the overall mission and reception (🧵):
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GenBio AI retweeted
Replying to @genbioai
@genbioai has released a preview of AIDO Cell—a stateful, multiscale world model designed to simulate cellular responses from DNA and RNA through proteins to whole-cell behavior. Early access for researchers is planned. businesswire.com/news/home/2… Subscribe to our newsletter and get the biggest biotech news straight to your inbox 🧬 syntheticbiologysummit.com/?…
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Correction on 20/ that should read "AIDO Cell," not "BAIDO Cell." Apologies for the typo.
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28/ Simulating the multi-scale, layer-spanning dynamics of a cell remains a challenge to both predict and validate. We are actively working to bridge the gap between what is functionally possible and what benchmarks exist in the field. Blog post and full report: genbio.ai/aido-cell-simulato…
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27/ Where it doesn't lead: AlphaGenome on ATAC, DNase and the RNA output tracks, AlphaFold3 on protein-DNA, isoDDE on protein-ligand docking. AIDO Cell is also pushing into territory that no existing model attempts.
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26/ On Virtual Cell Benchmark 1.0: AIDO Cell is state of the art on 24 of 31 metrics across five task families, and the only system covering all five.
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25/ We built AIDO Foundry to make the process of adapting AIDO Cell to new biological contexts seamless, and we're searching for academic partners to work with us on creating a complete virtual cell bank.
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