AI Automation of Commodities Trading
Geneva
Joined May 2020
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MedCommodities retweeted
it's crazy to this day that companies don't invest in their own AI inference and run everything on the cloud instead
meanwhile my little golden nvidia boxes are just token maxxing all day long
MedCommodities retweeted
Beans premiums Fob Brz closed surprisingly firm. BRLUSD above 5.60 and board rally. The FS today was the best since Sep.
MedCommodities retweeted
Pour donner un ordre d'idée, le Canada affiche désormais un fort déséquilibre entre hommes et femmes parmis les 20-29 ans, il est encore plus marqué que celui observé en Chine, en Inde ou au Pakistan.
Là où certains pays ont créé ce déséquilibre par les avortement sélectifs, le Canada l'aura accentué à coups d'immigration principalement masculine venant du tiers monde.
L'Inde présente un surplus masculin astronomique, de près de 40 millions d'hommes. La majeure partie de ce déficit féminin se concentre au Pendjab, dans le nord du pays, l'un des pires endroits au monde où naître femme. La Chine connaît également un déséquilibre, quoique dans une moindre mesure.
Je soupçonne par ailleurs que ces chiffres soient sous-estimés. Le problème, c'est que l'Inde peut (et a tout intérêt pour calmer la situation intérieure) ensuite exporter ce surplus masculin à l'étranger, ce qui contribue aussi à déséquilibrer le ratio hommes-femmes dans les pays d'accueil (Canada, etc.).
MedCommodities retweeted
ABSTRACT
Persistent SARS-CoV-2 spike protein after mRNA vaccination and after infection has been linked to a broad range of chronic pathology, yet the structural basis of that persistence is frequently described imprecisely
This analysis examines the sequence features that render spike prion-like, the intracellular processes that convert those features into destructive protein species, and the downstream consequences for transcriptional stability, host proteostasis, and tissue integrity
A critical distinction underlies this analysis: SARS-CoV-2 is a laboratory-synthesized recombinant virus, not a product of natural evolution
Its spike glycoprotein carries intrinsic prion-like domains that are present after both infection with the recombinant virus and prolonged expression from nucleoside-modified mRNA vaccines; therefore, spike is prion-like after both infection and mRNA vaccination
There is no direct evidence that intact spike is a classical self-replicating prion
The prion-like designation rests on sequence features that enable β-sheet aggregation and cross-seeding of host amyloids
Critically, once recombinant spike enters the interior of the cell, two processes become decisive determinants of pathology:
(1) trafficking through the endoplasmic reticulum (ER) induces ER stress and the unfolded protein response, driving proteolytic fragmentation and release of aggregation-prone fragments; and
(2) ribosomal frameshifting (programmed viral frameshifting and N1-methylpseudouridine-induced +1 frameshifting) generates aberrant, out-of-frame polypeptides
The combination of ER fragmentation and ribosomal shifts inside the cellular machinery is a critical determinant that markedly increases production of self-templating fibrous aberrant proteins
Spike elements are detected for months to years after both infection and vaccination
We have previously documented long-term (years) persistence of vaccine-derived spike, residual mRNA and plasmid elements, genomic integration events, transcriptomic and gene-expression alterations, and fatal myocarditis through joint Neo7Bioscience–McCullough Foundation surveillance
Building upon earlier work on spike-driven NF-κB activation, neuroinflammation, and proteolytic detoxification strategies, we synthesize the mechanisms by which recombinant spike initiates destructive protein formation, threatens transcriptional fidelity, and amplifies proteostatic collapse via cross-seeding
The cellular prion protein is itself a candidate target:
a five-residue spike sequence (YQAGS) differs by one residue from YQRGS in its globular C-terminal domain, and a case series has reported 26 patients in whom Creutzfeldt-Jakob disease began a mean of 11.38 days after COVID-19 vaccination, on a timescale sharply compressed relative to classical sporadic disease
Cross-seeding is not restricted to neural proteins
Thioflavin T-positive amyloid microclots have been detected in every participant of a recent cohort in which 94% had received COVID-19 mRNA vaccination and no participant had laboratory-confirmed prior infection, and purified spike alone converts fibrinogen into insoluble, fibrinolysis-resistant amyloid aggregates
In parallel, multi-year surveys of 808 embalmers across five countries document large white fibrous intravascular casts in a substantial fraction of the deceased, and Raman micro-spectroscopy of representative specimens shows stage-dependent β-sheet enrichment distinct from conventional postmortem thrombi
Enzymatic dissolution combined with precision molecular intervention via patient-specific ITI-PES peptides offers a rational therapeutic approach
Taken together, these findings define persistent recombinant spike as a potent prion-like driver of proteostatic collapse, pathological cross-seeding, transcriptional instability, and progressive tissue dysfunction across multiple organ systems
MedCommodities retweeted
Keywords
• SARS-CoV-2 spike protein • mRNA vaccination
• prion-like domains
• amyloid-β
• tau
• cross-seeding
• proteostasis
• endoplasmic reticulum stress
• ribosomal frameshifting
• amyloid microclots
• fibrinogen β-sheet aggregation
• transcriptional instability
MedCommodities retweeted
thread: peer-reviewed & published article
“Recombinant SARS-CoV-2 Spike Protein and Prion-Like Domains: Persistent Cross-Seeding of Amyloid-β and Tau, Transcriptional Instability, and Tissue Dysfunction”
John A. Catanzaro, NMD, PhD et al
DOI: doi.org/10.23958/ijirms/vol1…
Published: September 11, 2026
ALT doi.org/10.23958/ijirms/vol11-i09/2228
MedCommodities retweeted
Russia’s Ust-Luga port is ablaze after a large-scale drone attack tonight.
Ust-Luga is a major energy export hub — and now the main Russian #grain export port on the Baltic.
It’s interesting that this is happening right in the middle of the Abu Dhabi negotiations.
The last major confirmed attack on Ust-Luga was on September 1.
Quite a backdrop for day two in Abu Dhabi.
#Russia #blacksea #oatt #sizovreport #wheat
MedCommodities retweeted
Based on satellite imagery, three vessels are currently on fire in the Strait of Hormuz…
MedCommodities retweeted
🌽U.S. corn yield fell to 179.6 bpa this month, driven by declines in major states.
Despite a huge increase in Minnesota, Illinois and Indiana yields fell substantially, as did yield in Nebraska after last month's ear count controversy.
MedCommodities retweeted
In case you missed it, yesterday, I introduced and read Articles of Impeachment against @SecWar Hegseth. Today, the House will take the first procedural vote on these articles.
MedCommodities retweeted
🚨 BOMBSHELL COURT EVIDENCE EXPOSES A SCANDAL OF SECRECY, DECEPTION CONCERNS, AND DOCUMENTED JOINT-DEFENSE COORDINATION INVOLVING KRISTIN KNOUSE, RUTH LEHMANN, THE WHITEHEAD INSTITUTE, AND HHMI IN THE DAVID M. SABATINI ORDEAL.
A confidential financial settlement. Payments to Kristin Knouse and her lawyers. Legal protections extending to Ruth Lehmann. Documented joint-defense coordination. And an explicit provision restricting disclosure of the agreement to David Sabatini.
🔱 The ScienceGuardians™ Legal and Investigative Team has obtained the six-page settlement agreement filed in Massachusetts Superior Court on February 6, 2025.
The document reveals consequential arrangements involving Kristin Knouse, the Whitehead Institute (@WhiteheadInst), the Howard Hughes Medical Institute (HHMI, @hhmi_science), and Whitehead Director and President Ruth Lehmann (@REMLehmann).
These are not speculations. The provisions appear in the court-filed agreement itself.
🔴 1. Whitehead and HHMI agreed to pay Kristin Knouse and contribute to her legal defense.
Section 1 establishes that Whitehead and HHMI agreed to jointly fund a settlement payment, including compensation to Knouse and a contribution toward her attorneys' fees and costs in connection with the Sabatini litigation.
The financial amounts are redacted in the court-filed agreement, although we believe the total settlement may have reached SEVEN figures.
How much money did Whitehead and HHMI actually commit to Knouse and her legal defense?
The scientific community deserves full transparency regarding the financial scale of these arrangements and the institutional justification for such payments.
🔴 2. Ruth Lehmann's leadership was expressly covered by the legal releases.
Section 2 establishes broad mutual releases between Knouse, Whitehead, and HHMI.
Whitehead's release expressly includes its directors and senior administration, specifically naming Ruth Lehmann.
These provisions were not limited to an informal understanding between Knouse and her former employer. They created formal contractual protections extending across the participating institutions and their leadership.
🔴 3. Knouse, Whitehead, and Lehmann agreed to continue their joint defense.
Section 4 is particularly revealing.
It expressly provides for continuing cooperation between Knouse and Whitehead, including its senior administration and Ruth Lehmann, concerning matters related to Sabatini's lawsuit.
The agreement further states:
“Whitehead and Dr. Knouse further agree to continue to work pursuant to their common interest and joint defense privilege in the context of the Sabatini Lawsuit.”
Their lawyers were also expected to cooperate and share work where practicable.
The document therefore establishes not only financial arrangements but also an explicit commitment to continued legal cooperation between Knouse and Whitehead's leadership.
🔴 4. The agreement expressly restricted disclosure to David Sabatini.
Section 5 contains one of the document's most consequential provisions:
“This Agreement shall not be provided to Dr. Sabatini unless required by law.”
The same section establishes procedures allowing parties to seek protective orders in response to compulsory disclosure requests.
A financial settlement and continuing joint-defense agreement, expressly restricted from disclosure to the very scientist who was litigating against these parties.
The existence of this restriction demands serious examination of what was disclosed during litigation, when it was disclosed, and whether Sabatini received the information to which he was legally entitled.
🔴 5. Whitehead and HHMI expressly denied liability while agreeing to the payments and releases.
Section 6 characterizes the settlement as a compromise of disputed claims, intended to avoid further expense, and expressly disclaims any admission of liability.
The absence of an admission does not erase the financial payments, mutual releases, continuing joint defense, or disclosure restriction documented in this agreement.
⚠️ Ruth Lehmann and Whitehead's leadership must answer for these arrangements.
This court-filed document raises substantial questions about the financial and legal relationships among the individuals and institutions involved in Professor @DMSabatini's ordeal.
📑 EXAMINE THE ORIGINAL COURT EVIDENCE: All SIX pages of the settlement agreement are provided individually in high resolution in the thread below. Scroll down to examine the documented provisions firsthand.
🔱 ScienceGuardians™ Legal and Investigative Team
MORE COURT EVIDENCE. MORE REVELATIONS. STAY TUNED. ⚠️
@SciGuardians 🔱
🚨 “I LOST EVERYTHING.” — PROFESSOR DAVID M. SABATINI RECOUNTS THE DEVASTATING DESTRUCTION OF HIS SCIENTIFIC CAREER AND PROFESSIONAL LIFE.
FROM A WORLD-RENOWNED SCIENTIST AND POTENTIAL NOBEL PRIZE CONTENDER TO YEARS OF PROFESSIONAL, FINANCIAL, AND PERSONAL DEVASTATION.
> Become one of the world's leading biomedical scientists.
> Make pioneering discoveries concerning the mTOR signaling pathway, transforming our understanding of cell growth, metabolism, and disease.
> Build an internationally recognized laboratory and research program.
> Become an HHMI Investigator.
> Receive the prestigious 2020 Sjöberg Prize.
> Be widely regarded as a potential future Nobel Prize contender.
> Have a consensual relationship with fellow MIT scientist Kristin Knouse.
> Face allegations of sexual misconduct and an institutional investigation.
> August 2021: Lose his position at the Whitehead Institute.
> Lose his Howard Hughes Medical Institute (HHMI) Investigator appointment.
> Lose his principal source of research funding through HHMI.
> Lose his income, which he testified fell to ZERO within hours.
> Lose his laboratory and the institutional infrastructure supporting his research.
> Lose all his positions at biotechnology companies he helped establish.
> Lose his positions on biotechnology companies' scientific advisory boards.
> Lose prospective company shares and equity compensation.
> Lose more than 2 MILLION company shares, according to evidence presented by his legal team.
> Lose every position he held on scientific journals' editorial boards.
> Lose control over manuscripts being prepared by his research group.
> Lose direct communication with journal editors concerning those manuscripts.
> Have his institutional affiliations removed from scientific manuscripts, leaving his name without institutional contact information.
> 2022: Lose his tenured faculty position at MIT.
> Lose the opportunity for a potential appointment at New York University (NYU).
> Lose access to established research funding opportunities.
> Lose scientific collaborations and professional opportunities.
> Lose speaking invitations and opportunities to participate in the scientific community.
> Suffer an estimated $1.9 MILLION in lost income between 2021 and 2025, according to his legal team.
> Experience years of reputational destruction and professional isolation.
> Struggle to obtain employment despite his scientific accomplishments.
> Endure public humiliation, including an incident in which a fellow airline passenger reportedly requested to be moved after recognizing him.
> Endure profound personal suffering, including a suicide attempt he subsequently described publicly.
> Fight for years through the courts to obtain accountability.
> October 2026: A Massachusetts jury finds Kristin Knouse liable for defamation and tortious interference, awarding Sabatini $6 MILLION in damages.
🚨 BUT A JURY VERDICT CANNOT RESTORE EVERYTHING HE LOST.
His scientific positions. His research funding. His biotechnology interests. His editorial appointments. His manuscripts. His professional reputation. Years of his scientific career.
THE HUMAN SUFFERING AND LOST SCIENTIFIC OPPORTUNITIES EXTEND FAR BEYOND ANY FINANCIAL AWARD.
🚨 AND THE QUESTION OF INSTITUTIONAL ACCOUNTABILITY REMAINS UNRESOLVED.
Court evidence raises serious concerns about the decisions and conduct of Ruth Lehmann (@REMLehmann), Director and President of the @WhiteheadInst.
🔴 OCTOBER 2020: Kristin Knouse's private messages describe Lehmann as apparently contemplating Sabatini's dismissal months before the formal investigation began. The messages also refer to the importance of his “public outing” and the proposition that “noone is too successful to be taken down.”
🔴 DECEMBER 2020–AUGUST 2021: Court evidence includes private messages describing the diversity survey as a “cover up” for an investigation already being contemplated. The communications raise serious questions about the origins and transparency of Whitehead's investigative process.
🔴 MARCH 2021: Court evidence establishes that Lehmann received and acknowledged serious complaints describing investigators as “incredibly accusatory, aggressive” and “asking leading questions.”
🔴 AUGUST 2021: Testimony cited in Sabatini's court submissions raises the serious concern that Lehmann had decided to terminate Sabatini before receiving the investigators' final report, calling into question whether the outcome had been predetermined.
🔴 AUGUST–SEPTEMBER 2021: Communications between Lehmann and senior MIT leadership raise questions about institutional alignment and the independence of subsequent decisions.
🔴 SEPTEMBER–OCTOBER 2021: Additional court messages reveal discussions involving @MIT Professor Sangeeta Bhatia (@snbhatia) concerning the selection of MIT's tenure-review committee and possible pressure on MIT leadership, raising further questions about the independence of the process.
THESE DOCUMENTED CONCERNS DEMAND A FULL, INDEPENDENT ACCOUNTING OF THE ROLE OF WHITEHEAD'S LEADERSHIP IN THE DECISIONS THAT CONTRIBUTED TO SABATINI'S PROFESSIONAL LOSSES.
🚨 THE WHITEHEAD INSTITUTE BOARD MUST ACT.
A PUBLIC EXPLANATION, AN APPROPRIATE APOLOGY, AND FULL INSTITUTIONAL ACCOUNTABILITY ARE THE MINIMUM.
WHERE SERIOUS LEADERSHIP FAILURES ARE ESTABLISHED, RESIGNATION MUST FOLLOW.
🎥 WATCH PROFESSOR @DMSabatini DESCRIBE WHAT HE LOST IN HIS OWN WORDS.
🔱 ScienceGuardians™ Legal and Investigative Team
THE DEMAND FOR ACCOUNTABILITY IS GROWING. THE SCIENTIFIC COMMUNITY DESERVES ANSWERS. STAY TUNED. ⚠️
@SciGuardians 🔱
MedCommodities retweeted
This one hits home for me.
I worked with David while on the genome project.
My memories of Whitehead/MIT were some of the best years of my career. To be surrounded by excellence, Nobel laureates and world respected thought leaders was inspiring. To know you were in the right place at right time was the ultimate motivator.
In 1996-2000 we had an admin that opened doors and motivated the scientists to collaborate, publish papers, and pursue ruthlessly open science with transparency. We pushed boundaries with 24hour publication of sequence data to avoid data duplication and synchronize global sequencing efforts.
Whitehead was founded to remove the red tape of MIT and offer more independence and free inquiry.
That came with some eccentric minds you cant manage with hypocritical policies.
Late nights in the lab were the norm not the exception.
It was 24hr/day race.
Yes..
There were co-ed beer hours.
Work hard, play hard was not a woke sin in 1999.
As for the "Bro-culture".. far from it.
I recall many women occupying senior management roles on the genome project.
Lauren Linton-Director,
Nicole Stange-Thomann-ran Library Construction,
Jennifer Baldwin- ran Finishing,
Jill Mesirov ran BIFX.
We had no DEI policy. Pure meritocracy and it worked. Politics were simpleton distractions.
What do we see now?
David has been destroyed and it doesn't appear the horse they picked has published anything of significance since this drama unfolded. Both careers spun into a destructive tornado of hate and ruin.
I left Whitehead/MIT to found Agencourt Biosciences which delivered millions of dollars of royalties back to the Whitehead and they deserved every penny of it as without their incubator, the patent estate I filed with their backing would have been left to rust.
This company was acquired 6 years later by Beckman Coulter for $140M for its Whitehead invented SPRI patent estate, large book of business and its genomics center.
ApG was spun out of this acquisition to mature the SOLiD sequencer and this 19 person company was acquired by Applied Biosystems for $120M a year later in 2007. Another race with Illumina began. Competition forces you hire only the best and you don't have time to care about their gender, skin color or religion. You care about results.
We didn't need a DEI program to name all the 1st SOLiD sequencers after unappreciated women scientists. After all, Rosalind Franklin was instrumental in understanding the double helix. It was institutions that created that bias in 1952 with gender segregation at Kings College and it appears Whitehead is now trying to correct for it with the exact reverse sexism in 2020.
(For those not intimate with the history, the Sr Common Room at Kings College was exclusively male and many scientific discussions occurred without women 'peers').
If your pursuit of the truth requires unethical policies, you have lost the plot.
Bring back the race. Bring back the meritocracy. And like all good science, course correct quickly or fall behind. Failure to correct will leave this Knouse around your neck for decades.
MedCommodities retweeted
This is the “we don’t like the law, so we aren’t going to follow it” argument. That’s not how our Republic works - Presidents don’t get to choose the laws they follow and SCOTUS hasn’t struck down this law. Furthermore the executive branch follows other provisions of this law.
MedCommodities retweeted
IMPEACHMENT, Article III
The law requires our military to withdraw from hostilities within 60 days if Congress does not authorize the activity.
Operation Epic Fury has been underway for 256 days. Congress has not authorized it.
Hegseth is breaking the law.
Not even debatable.
MedCommodities retweeted
Ze Woke Cult canceled many people, when are we going to cancel them?
🤖 Made with AI
MedCommodities retweeted
All trade estimates for USDA's supply & demand reports due Tuesday at 11am CT. U.S. corn and soybean production continue to be the main numbers to watch.
On average, corn & soybean yields tend to move *more* in November than in October. Quiet report not guaranteed.
MedCommodities retweeted
Division by Zero f$cks is not undefined.
It equals Massie
