Assistant professor at Indiana Alzheimer’s Disease Research Center. Brain network analysis using fMRI, MEG and EEG in Alzheimer’s disease.
Indianapolis, IN
Joined July 2014
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Meichen Yu retweeted
An 𝐚𝐧𝐚𝐭𝐨𝐦𝐢𝐜𝐚𝐥 𝐜𝐨𝐧𝐧𝐞𝐜𝐭𝐢𝐯𝐢𝐭𝐲 𝐦𝐚𝐩 is a map of reconstructed white-matter pathways in the human brain based on diffusion-weighted MRI sequences.
To learn more about this NEJM Illustrated Glossary term, read the 2018 Review Article “Mapping Symptoms to Brain Networks with the Human Connectome”: nej.md/2FYkgAc
Explore more terms: nej.md/glossary
#Neurology
ALT Visual representation of an anatomical connectivity map
Meichen Yu retweeted
New Nature Communications paper! We developed the first MRI-based atlas mapping neurotransmitter disruptions in stroke, opening doors for personalized treatments.
Full article: rdcu.be/edHcH
#Neuroscience #StrokeResearch #MRI #Neurotransmitters
Meichen Yu retweeted
A chance to join our Centre for Neurotechnology, Neuromodulation, and Neurotherapeutics by applying for a Newton postdoctoral fellowship from the Royal Society.
If you are interested in 11.7T human MRI, OPM-MEG, noninvasive neuromodulation (e.g. focused ultrasound), or mental health let us know...
The Royal Society's Newton International Fellowships are now open for applications. These fellowships are for non-UK early career scientists who wish to conduct research in the UK. Find out more, including how to apply: #RSGrants royalsociety.org/grants/newt…
Meichen Yu retweeted
So excited to share that DeepPrep is now online in @naturemethods! 🚀 It’s 10× faster than the SOTA pipeline and more robust in handling clinical cases. We’ve just released v25.1.0 with a concise GUI and support for both Win and Linux. Give it a try! 📷 shorturl.at/0pB4H
🚀Excited to share our #preprint on DeepPrep: a high-speed, scalable preprocessing pipeline for s/fMRI, empowered by SOTA #deeplearning algorithms. What takes #fMRIPrep 7 hrs, DeepPrep achieves in just 40 mins! Dive into the details🧵 @hesheng3 @sattertt
shorturl.at/eBEP8
Meichen Yu retweeted
After 5 years of data collection (179 first-time mothers + controls), and 2 years of data analyses and article writing, the first @BeMotherProject paper is out! We uncovered a U-shaped trajectory in maternal GM volume, resolving a long-standing puzzle in the maternal brain field.
Can’t believe our new @NatureComms paper is out! ✨🧠🤰
We tracked a cohort of 179 women before, during, and post-pregnancy, revealing a U-shaped trajectory in the mother’s brain structure linked to steroid hormone fluctuations and maternal attachment.
#ParentalBrain
🧵👇
Meichen Yu retweeted
New study in BMC Medicine examines how childhood socioeconomic status (SES) influences brain development. It highlights links between SES and variations in cortical regions, impacting cognitive and emotional growth into adulthood. bit.ly/3CWPtlb @runsenchen @zaixucui
Meichen Yu retweeted
Linking post-mortem cell-type distributions with the in vivo functional organization of the human cerebral cortex, as assessed through fMRI
@XihanZhang1 @AvramHolmes @KevinMAnder @SidChop @elvisha9 @MarkGerstein @DanielMargulies @HolmesLab_BHI
nature.com/articles/s41593-0…
Meichen Yu retweeted
Temporal lobe epilepsy may be a network disorder, and treatments might be improved by looking beyond the disease epicenter in the hippocampus. ja.ma/4fEKbck
Meichen Yu retweeted
A new FSLeyes is out, with a couple of new line vector options, including the ability to modulate vector length by another image. Details at open.win.ox.ac.uk/pages/fsl/…, instructions at fsl.fmrib.ox.ac.uk/fsl/docs/…
Meichen Yu retweeted
Integrating brainstem and cortical functional architectures | nature.com/articles/s41593-0…
led by @JustineYHansen in @NatureNeuro
400 cortical regions + 58 brainstem nuclei. Lesgo 🤘🕶️⤵️
Meichen Yu retweeted
First paper describing the Franco-German 11.7T Iseult scanner out in @naturemethods. While the image comparison figure is certainly a strawman (I’ve seen much better images acquired at 3 and 7T), this is still a fascinating technical advance:
nature.com/articles/s41592-0…
Meichen Yu retweeted
People who are fitter than others—measured by their maximum rate of oxygen consumption, or VO2max—have greater cerebral myelination, particularly in middle-aged and older adults, which may protect against neurodegenerative diseases such as Alzheimer’s. ow.ly/s9K350T50pn
ALT Examples of axial and sagittal myelin water fraction parameter maps averaged across participants with either lower, moderate, or higher VO2max levels. Results are shown for representative slices. Visual inspection indicates that, overall, participants with higher VO2max levels exhibit greater regional myelin water fraction values, especially at middle and older ages.
Meichen Yu retweeted
Science behind the Study: Brain–Computer Interfaces for Restoring Communication nej.md/46ZSpc5
#Neurology
ALT Decoding Speech or Click Signals from Brain Activity to Restore Communication.
Meichen Yu retweeted
🍄 Psilocybin & escitalopram create different reconfigurations in the global functional hierarchy of 🧠 brain dynamics in people with major depressive disorder 👇
@HedoniaResearch @RCarhartHarris @ysanz6
nature.com/articles/s44220-0…
Meichen Yu retweeted
🔥Years in the making, now published! My final postdoc project in @NatureComms shows that Tau and TSPO PET follow gradients🌈 of connectivity in #Alzheimer disease 🧠
nature.com/articles/s41467-0…
Thanks to @alzassociation @Sunnybrook @MCSA_Montreal
Now ready for new adventures!🌍☺️
Meichen Yu retweeted
📢OPEN PHD POSITION 📢
Looking for a PhD and interested in neuromodulation?
Then come work with me, @_PetraRitter and the @Retune_CRC community on modeling deep brain stimulation from a network-science perspective 😊
Please retweet!
@BrainModes @ChariteBerlin @BIH_Innovation
Meichen Yu retweeted
It was an honor to represent the CLEAR-AD consortium at the NIA-AA Precision Medicine pre-conference at AAIC! Clear-AD.org will have regular updates.
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Meichen Yu retweeted
Clinical Practice: Management of Insomnia nej.md/3zMCiBW
ALT Table 3. Psychological and Behavioral Therapies for Patients with Insomnia.
ALT Table 4. Medications for the Treatment of Insomnia.