Sanjay Chandriani (@sanjayofSF) header
Sanjay Chandriani (@sanjayofSF) profile picture

Curious dad, friend, scientist

San Francisco
Joined September 2014
Photo by Sanjay Chandriani (@sanjayofSF)Photo by Sanjay Chandriani (@sanjayofSF)Photo by Sanjay Chandriani (@sanjayofSF)Photo by Sanjay Chandriani (@sanjayofSF)Photo by Sanjay Chandriani (@sanjayofSF)Photo by Sanjay Chandriani (@sanjayofSF)Photo by Sanjay Chandriani (@sanjayofSF)
Sanjay Chandriani retweeted
Today, we're excited to announce we have initiated the global clinical development program for TRCN-1023, an investigational antisense oligonucleotide designed to restore UNC13A protein function for the treatment of #ALS. CEO @ercgrn shares insight below. traceneuro.com/uncategorized…
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Sanjay Chandriani retweeted
1 in 400 people around the world will be diagnosed w/ #ALS in their lifetime. Meet Trace - on a mission to expand the promise of genomic medicine for those w/ neurodegenerative diseases, re-establishing healthy communication between nerves & muscle cells. businesswire.com/news/home/2…
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The Swimmers g.co/kgs/AYxsaE — a remarkably moving film that captures the desperation, heartbreak, loss, love, luck, and triumph of Syrian refugees
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Sanjay Chandriani retweeted
Camzyos approval a milestone for HCM patients and exemplar for translating human genetics -> medicines. How can we apply this to more diseases? A few insights:
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Sanjay Chandriani retweeted
Parents have to choose their battles. 8 fights worth picking with your kids:
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Sanjay Chandriani retweeted
RT if you support my legislation to ban members of Congress from selling and trading stocks.
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Unbeknownst to us, our @amtrak train was posted to the wrong track out of NY Penn station. Only after the train started to move did we realize we were on the wrong train. The official @amtrak response was totally unhelpful and unsympathetic. 1/2
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The (wrong) train’s crew members, however, were awesome — they identified another train we could intercept in Stamford and called the crew of that train to arrange our transfer. @amtrak customer service phone operators could use a lesson from the crew on train #148. 2/2
Sanjay Chandriani retweeted
Replying to @Bob_Wachter
Do you have data on how the virus is impacting younger children who aren't vaccinated, both in infection rate but also severity of symptoms? Reading a lot of worrying comments in local parent groups.
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Happy to see this work published! While the project didn't end in quite the way we wanted, we learned some interesting glycosphingolipid biology along the way.
Excited to share our study in which we evaluate CGT inhibition to reduce GalCers and sulfatides for the treatment of Krabbe disease and MLD. #BioMarin #WUSTL <nature.com/articles/s41598-0…> A thread... 1/17
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Sanjay Chandriani retweeted
Excited to share our study in which we evaluate CGT inhibition to reduce GalCers and sulfatides for the treatment of Krabbe disease and MLD. #BioMarin #WUSTL <nature.com/articles/s41598-0…> A thread... 1/17
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Cell-Mediated Immunity to NAGLU Transgene Following Intracerebral Gene Therapy in Children With Mucopolysaccharidosis Type IIIB Syndrome ncbi.nlm.nih.gov/pmc/article… #SanfilippoB #MPSIIIB (AMT-110 $QURE suspended this program in 2016)
Sanjay Chandriani retweeted
If we used the 16S/18S rRNA cutoff of >97% identity to define species in eukaryotes, the following taxa would be in the same species with humans: chimpanzees (99.99% id) moles (99.95%) bats (99.52%) pangolins (99.04%) rabbits (98.19%) (Analysis by Doug Rusch)
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Sanjay Chandriani retweeted
Maze Therapeutics Reveals Its Initial Three Lead Programs Targeting Underlying Genetic Drivers of Life-Threatening Diseases finance.yahoo.com/news/maze-… via @Yahoo
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Sanjay Chandriani retweeted
More than two years after emerging from stealth mode with $191 million, a guild of prestigious scientific founders and support from some top-flight VCs, Maze Therapeutics is finally ready to unveil what they’ve been up to. endpts.com/exclusive-maze-un…
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Sanjay Chandriani retweeted
1/14 How does fever help us fight infections? For millennia, fever has been recognized as a beneficial response to invading pathogens. If this is so, why don't we have a resting temperature of 102°F (38.9°C)? Wouldn't that protect us even better? Let's have a look.
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