@GavinHa

Associate Professor and Computational Biologist studying cancer genomics & liquid biopsies @fredhutch

 Seattle, WA
GavinHaLab.org/
Joined April 2009
  • Tweets205
  • Following340
  • Followers1.1K
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Published today in @Nature: A new Fred Hutch study using a first-in-kind rapid autopsy program shows details of metastatic bladder cancer subtypes; could improve diagnosis and future treatment. bit.ly/4xrNFra @pushpa_itagi @HsiehLab @GavinHa @DrOmarMian

Study uncovers genomic architecture and natural history of metastatic bladder cancer

A new study published in Nature has established the foundational landscape of tumor evolution in bladder cancer and differences in the cancer subtypes, which could point toward better diagnosis and...

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Gavin Ha retweeted
Hsieh Lab@HsiehLabSep 16
This work was led by @GavinHa , @HsiehLab, Ming Lam, and @DrOmarMian, involving 5-years of tissue collection followed by 5-years of analysis. The UW/Fred Hutch Rapid Autopsy Program was founded by Drs. @JLWrightMD, Bruce Montgomery, Ming Lam, Funda Vakar-Lopez, @HsiehLab
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Gavin Ha retweeted
Hsieh Lab@HsiehLabSep 16
Ever wonder how heterogeneity defines bladder cancer subtypes? Ha and Hsieh Lab postdoctoral fellows @pushpa_itagi and Samantha Schuster @fredhutch did, leading to a deep study of bladder cancer clonality, evolution, and heterogeneity published @Nature nature.com/articles/s41586-0…

Evolution and heterogeneity of lethal metastatic bladder cancer subtypes

Nature - A rapid autopsy programme provides valuable resources to enable detailed molecular and genetic analyses of the temporal evolution of aggressive histological subtypes and therapy resistance...

nature.com
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Thrilled to see our work over years in #bladdercancer published in @Nature THANKS to patients/families consenting to our research autopsy program wanting to support others! Kudos to @HsiehLab @GavinHa #OmarMian #MingLam et al. @fredhutch @HutchPresident nature.com/articles/s41586-0…

Evolution and heterogeneity of lethal metastatic bladder cancer subtypes

Nature - A rapid autopsy programme provides valuable resources to enable detailed molecular and genetic analyses of the temporal evolution of aggressive histological subtypes and therapy resistance...

nature.com
Fred Hutch Cancer Center@fredhutchSep 17
Published today in @Nature: A new Fred Hutch study using a first-in-kind rapid autopsy program shows details of metastatic bladder cancer subtypes; could improve diagnosis and future treatment. bit.ly/4xrNFra @pushpa_itagi @HsiehLab @GavinHa @DrOmarMian

Study uncovers genomic architecture and natural history of metastatic bladder cancer

A new study published in Nature has established the foundational landscape of tumor evolution in bladder cancer and differences in the cancer subtypes, which could point toward better diagnosis and...

fredhutch.org
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In a step toward a #liquidbiopsy for small cell #lungcancer, a Fred Hutch team led @DMacPhersonLab and @GavinHa have developed an approach that can distinguish several #SCLC subtypes from blood samples. bit.ly/3TUvFUr
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So excited to share our work on tumor genomes of African ancestry in common cancers. We report several actionable associations, including a novel ancestry-smoking interaction impacts TP53 rate. More discoveries to come if we improve diversity in genomics! cell.com/cancer-cell/fulltex…

Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across...

By leveraging two large genomic cohorts, Jiagge et al. characterize genomic alterations and clinically relevant biomarkers in patients with African ancestry across six common cancers. They identify...

cell.com
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Congrats to Robert Patton for being awarded the @PCF_Science 2023 Young Investigator Award & achieving the top scoring application! Honored to be his co-mentor with PeteNelson. #PCFRetreat23
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Gavin Ha retweeted
Manu Setty@SettyM29 Aug 2023
The #MahanFellowship supports young scientists in the early stages of their careers. We offer fellows a 21-month stipend as they pursue their proposed research project, alongside a mentor in one of our Herbold Computational Biologist labs. Apply today: apply.interfolio.com/130340
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Have you ever wondered if 3’UTR point mutations found in cancer patients matter? We’re excited to share our new publication out today @CellReports, where we’ve defined how prostate tumor 3’UTR mutations affect molecular & cellular oncogenicity. cell.com/cell-reports/fullte… 1/n
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Check out the Cancer Discovery papers highlighted in the new @AACR Journals collection, Liquid Biopsies. bit.ly/3WP1E9M @GavinHa
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Excited to share our recent work on KaryoCreate, a new method to engineer chromosome-specific gains and losses in human cells with @SteSantaguida and @GiuntaLab cell.com/cell/pdf/S0092-8674… Check out also recent similar and complementary work by @LensSusanne and @McClellandLab!
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Attending the Major Symposium at #AACR23 about Liquid Biopsy? See the related paper published in @CD_AACR: Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced #ProstateCancer Phenotypes by @GavinHa and @Navonilde aacrjournals.org/cancerdisco…
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Gavin Ha retweeted
Lee Lab@jklee_lab11 Apr 2023
Excited to share our paper @NatureComms on STEAP1 CAR T cell and tumor-localized IL-12 for prostate cancer: tinyurl.com/2ze4trzt Congrats to lead author @vipulbhatia24! Thanks to our collaborators @BioengIshihara @SaulPriceman @sriv4000 @fredhutch @Prostate_IPCR @PCF_Science.
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Fred Hutch is recruiting a faculty member for our #prostatecancer research program. Focus areas include primary prevention, etiology, genetics/genomics, epigenetics, tumor microenvironment, metastasis, development of novel therapeutics and more. Apply: apply.interfolio.com/121588
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Recently published: @gavinha et al. develop Griffin, a #computational framework for #tumor subtype classification based on #cfDNA #nucleosome profiling that can work with ultra-low pass #sequencing data #CancerResearch @natrescancer doi.org/10.1038/s41467-022-3…
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In the March issue of Cancer Discovery— Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced #ProstateCancer Phenotypes, by @Navonilde, Robert Patton, Peter Nelson, @GavinHa et al bit.ly/3mXpBhc @fredhutch #LiquidBiopsy #cfDNA #ctDNA
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📢Prostate Cancer Scientists (PhDs, MD/PhDs, or MD scientists) - join us at Fred Hutch! New lab-based PC position (wet or dry) posted! bit.ly/3Ela8gN Email Pete! ([email protected]) @PCF_Science @HsiehLab @jklee_lab @BurcuDarst @DanLinMD @fredhutch @PGrivasMDPhD
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Faculty position opening! Assistant or associate faculty professor in the @fredhutch Prostate Cancer Research Program! Broad research expertise considered (e.g., prevention, genetics/genomics, therapeutics): bit.ly/3Ela8gN @NewPI_Slack @FuturePI_Slack #prostatecancer
Jessica Hawley MD MS@JessicaHawleyMD18 Feb 2023
📢Prostate Cancer Scientists (PhDs, MD/PhDs, or MD scientists) - join us at Fred Hutch! New lab-based PC position (wet or dry) posted! bit.ly/3Ela8gN Email Pete! ([email protected]) @PCF_Science @HsiehLab @jklee_lab @BurcuDarst @DanLinMD @fredhutch @PGrivasMDPhD
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We have an open joint-postdoc position with @DMacPhersonLab to work on new computational approaches for studying #lungcancer using #liquidbiopsy. If you're interested in cancer genomics, LBx, AI or #PrecisionOncology, pls apply! careers-fhcrc.icims.com/jobs…
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Can an integrative approach reliably detect urine tumor DNA in localized #bladdercancer patients? We addressed this in our latest paper, out now in @Nature_npj Precision Oncology. nature.com/articles/s41698-0… @ZacharySmithMD @WashU_Uro @WashURadOnc @WashU_ctDNA @WashUDPS 1/15

Urine cell-free DNA multi-omics to detect MRD and predict survival in bladder cancer patients

npj Precision Oncology - Urine cell-free DNA multi-omics to detect MRD and predict survival in bladder cancer patients

nature.com
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